Europe — EMA
Metamizol Gemax Pharma
GNH USA supplies Metamizol Gemax Pharma (Metamizole Sodium), a pyrazolone analgesic and antipyretic for pain, fever and colic.
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What is Metamizole Sodium Monohydrate?
Metamizole sodium, the active ingredient in Metamizol Gemax Pharma, is a pyrazolone presented as an oral formulation for oral use. It is used to relieve pain, reduce fever, and treat colic in adult patients. GNH USA supplies Metamizol Gemax Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Metamizole Sodium Monohydrate used for?
Metamizol Gemax Pharma is indicated for conditions involving acute or severe pain, fever, and gastrointestinal colic. - Pain: provides analgesic relief for moderate to severe acute pain. - Fever: reduces elevated body temperature in febrile states. - Colic: alleviates painful intestinal or biliary colic episodes.
What are the side effects of Metamizole Sodium Monohydrate?
Metamizol Gemax Pharma may cause a range of adverse reactions, from mild to severe.
Common Side Effects: - Nausea: mild gastrointestinal upset. - Dizziness: transient light‑headedness. - Hypotension: occasional drop in blood pressure. - Rash: skin redness or itching. - Headache: mild to moderate intensity.
Serious or Rare Side Effects: - Agranulocytosis: severe reduction in white blood cells. - Anaphylactic reaction: life‑threatening allergy. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatotoxicity: liver injury indicated by elevated enzymes.
What precautions apply to Metamizole Sodium Monohydrate?
Before prescribing Metamizol Gemax Pharma, clinicians should consider several safety measures. - Renal function: assess kidney status in patients with impairment. - Hematologic monitoring: perform baseline and periodic blood counts. - Allergy history: avoid in individuals with known hypersensitivity to pyrazolones. - Concomitant myelosuppressants: use caution when combined with other bone‑marrow‑suppressing agents. - Pregnancy and lactation: evaluate risk‑benefit ratio; use only if clearly needed. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.
What does Metamizole Sodium Monohydrate interact with?
Metamizol Gemax Pharma can interact with several drug classes, requiring attention to avoid adverse outcomes.
Major Interactions (Avoid): - Other pyrazolones: increased risk of severe blood dyscrasias. - Anticoagulants: potential enhancement of bleeding tendency. - Immunosuppressants: additive bone‑marrow suppression.
Moderate Interactions (Monitor Closely): - NSAIDs: heightened gastrointestinal irritation. - CYP450 substrates: possible alteration of metabolic clearance. - Alcohol: may intensify hypotensive effects.
Frequently asked questions
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Product details
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