GNH USA

Europe — EMA

Metamizol Chalim

GNH USA supplies Metamizol Chalim (Metamizole Magnesium), a pyrazolone analgesic for pain and fever management. Request a quote for supply to hospitals.

Metamizole Magnesium

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What is Metamizole Magnesium?

Metamizole Magnesium, the active ingredient in Metamizol Chalim, is a pyrazolone analgesic presented as an oral tablet for oral use. It treats pain and fever in adults and children as directed by a healthcare professional.

GNH USA supplies Metamizol Chalim as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metamizole Magnesium used for?

Metamizole Magnesium is used to manage pain and fever by acting on prostaglandin-mediated pathways.

Pain: provides analgesic relief for mild to moderate acute pain Fever: reduces elevated body temperature Postoperative pain: controls pain after surgical procedures Cancer pain: offers analgesia for cancer‑related pain

What are the side effects of Metamizole Magnesium?

Metamizole Magnesium may cause a range of adverse reactions.

Common Side Effects: - Nausea or vomiting - Dizziness or light‑headedness - Skin rash or mild itching - Transient low white‑blood‑cell count - Mild hypotension - Headache

Serious or Rare Side Effects: - Agranulocytosis (severe drop in neutrophils) - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Anaphylactic shock - Severe blood dyscrasias - Hepatic dysfunction - Life‑threatening hypotension

What precautions apply to Metamizole Magnesium?

Before using Metamizole Magnesium, consider the following safety measures.

Renal impairment: use with caution and monitor kidney function Hepatic disease: avoid or adjust dose in patients with liver dysfunction History of blood disorders: contraindicated in individuals with prior agranulocytosis Pregnancy: only if clearly needed after risk‑benefit assessment Concurrent NSAIDs: increased risk of gastrointestinal toxicity Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

What does Metamizole Magnesium interact with?

Metamizole Magnesium can interact with other medicines; monitor the following.

Major Interactions (Avoid): - Co‑administration with other myelotoxic agents: heightened risk of severe blood dyscrasias - Combination with other NSAIDs: increased gastrointestinal bleeding risk - Use with ACE inhibitors or diuretics: may potentiate hypotensive effects

Moderate Interactions (Monitor Closely): - Warfarin: possible enhancement of anticoagulant effect, monitor INR - Lithium: may raise lithium plasma concentrations, monitor levels - Methotrexate: potential increase in toxicity, observe liver function

Frequently asked questions

What is Metamizol Chalim used for?+
Metamizol Chalim contains metamizole magnesium, a pyrazolone analgesic used to relieve moderate to severe pain and to reduce fever. It is commonly prescribed for postoperative discomfort, cancer‑related pain, and acute febrile episodes when other treatments are insufficient.
How does metamizole magnesium work?+
Metamizole magnesium works by inhibiting cyclooxygenase enzymes, which lowers prostaglandin production, and by modulating central pain pathways in the spinal cord and brain. This combined effect diminishes the perception of pain and helps lower elevated body temperature.
What is the usual dose of Metamizol Chalim?+
The appropriate dose of Metamizol Chalim is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly as directed.
Is Metamizol Chalim safe during pregnancy or breastfeeding?+
Safety of metamizole magnesium in pregnancy or lactation has not been fully established. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.
How do I order Metamizol Chalim from GNH USA?+
To order Metamizol Chalim, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Metamizol Chalim compare with other analgesics?+
Metamizole Chalim belongs to the pyrazolone class, offering strong analgesic and antipyretic effects with less anti‑inflammatory activity than traditional NSAIDs. Compared with drugs like ibuprofen or paracetamol, it may provide more rapid pain relief but carries a higher risk of rare blood‑related side effects, requiring careful monitoring.
What are the storage and handling requirements for Metamizol Chalim?+
Metamizol Chalim should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, direct sunlight, and excessive heat to maintain potency and stability throughout its shelf life.
How is Metamizol Chalim administered?+
Metamizol Chalim is administered orally, typically as a tablet that is swallowed with water. The exact administration schedule, including timing relative to meals, is determined by the prescribing clinician and should be followed as indicated on the prescription label.
What are the most serious risks associated with Metamizol Chalim?+
The most serious risks include agranulocytosis, a potentially life‑threatening drop in white‑blood‑cell count, and severe skin reactions such as Stevens‑Johnson syndrome. Patients should be monitored for signs of infection, unusual bruising, or skin changes, and seek immediate medical attention if these occur.
Who should not use Metamizol Chalim?+
Metamizol Chalim should be avoided in individuals with a known hypersensitivity to metamizole or other pyrazolones, those with a history of agranulocytosis, severe liver or kidney impairment, and patients for whom safer alternatives are available. A healthcare professional should evaluate suitability before prescribing.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metamizole Magnesium
Route
Oral Use
Manufacturer
Laboratórios Basi – Indústria Farmacêutica, S.A.
Origin
EU

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