GNH USA

Europe — EMA

Metamizol Basi (Metamizole Sodium Monohydrate)

GNH USA supplies Metamizol Basi (Metamizole), a pyrazolone analgesic for pain, fever and post‑operative relief. Request a quote for global supply.

Metamizole Sodium Monohydrate

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What is Metamizole Sodium Monohydrate?

Metamizole, the active ingredient in Metamizol Basi, is a pyrazolone analgesic presented as an injectable solution for intramuscular or intravenous use. It is employed to manage pain and fever, particularly in postoperative settings and acute care patients.

GNH USA supplies Metamizol Basi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metamizole Sodium Monohydrate used for?

Metamizol Basi is used for conditions where rapid analgesic or antipyretic control is required.

- Pain: Provides analgesic relief for moderate to severe acute pain. - Fever: Reduces elevated body temperature in febrile states. - Post‑operative analgesia: Controls pain and fever after surgical procedures.

What are the side effects of Metamizole Sodium Monohydrate?

Metamizol Basi may be associated with a range of adverse reactions.

Common Side Effects: - Injection site pain: Discomfort at the site of administration. - Nausea: Mild to moderate feeling of queasiness. - Dizziness: Transient light‑headedness. - Hypotension: Temporary drop in blood pressure. - Rash: Mild skin erythema.

Serious or Rare Side Effects: - Agranulocytosis: Severe reduction in white blood cells. - Anaphylaxis: Immediate hypersensitivity reaction. - Stevens‑Johnson syndrome: Severe mucocutaneous eruption. - Hepatotoxicity: Liver enzyme elevation or injury. - Hemolytic anemia: Destruction of red blood cells.

What precautions apply to Metamizole Sodium Monohydrate?

When using Metamizol Basi, consider the following safety measures.

- Indication review: Confirm appropriate use for pain or fever. - Blood monitoring: Periodic complete blood counts to detect agranulocytosis. - Allergy assessment: Screen for known hypersensitivity to pyrazolones. - Pregnancy and lactation: Use only if benefits outweigh potential risks. - Renal/hepatic function: Adjust use in patients with organ impairment. - Store below 25°C: Keep in original container, protect from light and moisture.

What does Metamizole Sodium Monohydrate interact with?

Metamizol Basi can interact with several medication classes.

Major Interactions (Avoid): - Anticoagulants: Increased bleeding risk. - Other pyrazolone or NSAID agents: Heightened risk of agranulocytosis. - Immunosuppressants: Potential additive bone‑marrow suppression.

Moderate Interactions (Monitor Closely): - ACE inhibitors: May enhance hypotensive effect. - Diuretics: Possible additive blood pressure lowering. - Corticosteroids: Monitor for enhanced immunosuppression.

Frequently asked questions

What is Metamizol Basi used for?+
Metamizol Basi is an injectable pyrazolone analgesic indicated for the treatment of moderate to severe acute pain, reduction of fever, and management of postoperative discomfort in hospital or clinical settings.
How does Metamizole work in the body?+
Metamizole inhibits cyclooxygenase enzymes, decreasing prostaglandin synthesis, and also modulates central spinal pathways, providing combined analgesic and antipyretic effects without the typical gastrointestinal impact of many NSAIDs.
What is the usual dose of Metamizol Basi?+
The specific dose and administration schedule of Metamizol Basi are determined by the prescribing clinician based on the patient’s condition, weight, and clinical response. No standard dosing is provided here.
Is Metamizol Basi safe during pregnancy or breastfeeding?+
Safety data for Metamizole in pregnancy and lactation are limited. It should only be used when the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.
How do I order Metamizol Basi from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.
How does Metamizol compare with other analgesics?+
Metamizole offers analgesic and antipyretic effects similar to NSAIDs but with a lower incidence of gastrointestinal irritation. However, it carries a rare risk of agranulocytosis, which is less common with many other analgesic classes, so risk‑benefit assessment is essential.
What are the storage requirements for Metamizol Basi?+
Metamizol Basi should be stored below 25 °C, in its original packaging, protected from light and moisture. Do not freeze the product, and keep it out of reach of children.
How is Metamizol Basi administered?+
The medication is supplied as a sterile injectable solution and may be given intramuscularly or intravenously by a qualified healthcare professional, following aseptic technique and appropriate dilution if required.
What are the most serious risks associated with Metamizol Basi?+
The most serious adverse reactions include agranulocytosis, anaphylactic shock, Stevens‑Johnson syndrome, and severe liver injury. Immediate medical attention is required if signs of these conditions appear.
Who should not use Metamizol Basi?+
Patients with known hypersensitivity to pyrazolones, a history of agranulocytosis, severe liver or kidney impairment, or those receiving concurrent myelosuppressive therapy should avoid Metamizol Basi unless specifically directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metamizole Sodium Monohydrate
Route
Intramuscular Use , Intravenous Use
Manufacturer
Laboratórios Basi – Indústria Farmacêutica, S.A.
Origin
EU

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