Metamizol Auxilto

Metamizole sodium, the active ingredient in Metamizol Auxilto, is a pyrazolone derivative presented as an oral formulation for systemic use. It is employed to manage moderate to severe pain and to reduce fever in adult patients. The drug is classified as an analgesic and antipyretic and is available by prescription in the European market.

GNH USA supplies Metamizol Auxilto as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide.

Metamizole sodium is used for pain and fever management by inhibiting prostaglandin synthesis.

Moderate to severe pain: provides analgesic relief when other agents are insufficient. Postoperative pain: helps control pain after surgical procedures. Fever: reduces elevated body temperature in acute febrile states.

Metamizole sodium may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Vomiting: occasional episodes. - Dizziness: transient light‑headedness. - Skin rash: mild erythema.

Serious or Rare Side Effects: - Agranulocytosis: severe drop in white blood cells, potentially life‑threatening. - Anaphylactic reaction: rapid onset of hypersensitivity. - Severe hypotension: sudden drop in blood pressure. - Hepatotoxicity: liver enzyme elevation.

Precautions should be observed when prescribing Metamizole sodium.

Renal impairment: monitor kidney function. Hepatic disease: use with caution. History of blood dyscrasias: avoid if prior agranulocytosis. Concomitant anticoagulants: increased bleeding risk. Pregnancy and lactation: safety not established, weigh risks. Store at ambient temperature: keep in original packaging, protect from moisture and light.

Metamizole sodium can interact with several medicines, requiring careful assessment.

Major Interactions (Avoid): - Cyclooxygenase inhibitors (e.g., NSAIDs): increased risk of renal toxicity. - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Immunosuppressants (e.g., methotrexate): potential bone marrow suppression.

Moderate Interactions (Monitor Closely): - Diuretics: may enhance hypotensive effect. - Lithium: possible increase in serum lithium levels. - Corticosteroids: additive gastrointestinal irritation.