Europe — EMA
Metamizol Aristo (Metamizole Magnesium)
GNH USA supplies Metamizol Aristo (Metamizole Magnesium), a pyrazolone analgesic, antipyretic and spasmolytic for pain, fever and visceral colic.
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What is Metamizole Magnesium?
Metamizole magnesium, the active ingredient in Metamizol Aristo, is a pyrazolone presented as an oral formulation for systemic use. It is used to relieve pain, reduce fever, and alleviate visceral colic in adult patients under medical supervision.
GNH USA supplies Metamizol Aristo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Metamizole Magnesium used for?
Metamizol Aristo is employed in the management of conditions that involve acute pain, fever, or smooth‑muscle spasm.
- Pain: provides analgesic relief for moderate to severe acute pain. - Fever: reduces elevated body temperature in febrile states. - Visceral colic: eases spasm‑related discomfort in gastrointestinal or biliary colic.
What are the side effects of Metamizole Magnesium?
Metamizol Aristo may cause a range of adverse reactions, from mild to severe.
Common Side Effects: - Nausea: mild gastrointestinal upset. - Dizziness: transient light‑headedness. - Rash: skin erythema or mild itching. - Hypotension: occasional drop in blood pressure.
Serious or Rare Side Effects: - Agranulocytosis: severe reduction in white blood cells, requiring immediate medical attention. - Anaphylaxis: life‑threatening allergic reaction with airway compromise. - Hepatotoxicity: rare liver enzyme elevations or injury.
What precautions apply to Metamizole Magnesium?
When prescribing Metamizol Aristo, clinicians should consider several safety measures.
- Renal impairment: assess kidney function before use. - Hepatic disease: monitor liver enzymes during therapy. - Hematologic disorders: avoid in patients with a history of agranulocytosis. - Concomitant anticoagulants: watch for increased bleeding risk. - Pregnancy and lactation: use only if benefits outweigh potential risks. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.
What does Metamizole Magnesium interact with?
Metamizol Aristo can interact with other medicines, altering efficacy or safety.
Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding tendency. - Immunosuppressants (e.g., azathioprine): heightened risk of bone‑marrow suppression.
Moderate Interactions (Monitor Closely): - Other NSAIDs or pyrazolones: additive gastrointestinal irritation. - Diuretics: possible enhancement of hypotensive effect. - Lithium: may increase lithium serum levels.



