Mesalazine Mayoly

Mesalazine, the active ingredient in Mesalazine Mayoly, is an aminosalicylate presented as an oral tablet for oral use. It is indicated for the treatment of ulcerative colitis and Crohn's disease, providing anti‑inflammatory action in the colon of adult patients.

GNH USA supplies Mesalazine Mayoly as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable global distribution, ensuring product integrity through rigorous quality control and timely logistics.

Mesalazine is an aminosalicylate that acts locally in the colon to manage inflammatory bowel disease.

Ulcerative colitis: reduces mucosal inflammation and helps maintain remission. Crohn's disease (colonic involvement): controls inflammation and alleviates symptoms. Maintenance therapy in IBD: prolongs remission periods and decreases relapse frequency. Induction of remission in ulcerative colitis: achieves clinical response within weeks of therapy.

Mesalazine may cause a range of adverse reactions, which are categorized by frequency.

Common Side Effects: - Headache: mild to moderate headache reported. - Nausea: occasional feeling of nausea. - Abdominal pain: mild cramping or discomfort. - Flatulence: increased intestinal gas.

Serious or Rare Side Effects: - Severe hypersensitivity: rash, fever, or anaphylaxis requiring immediate medical attention. - Blood dyscrasias: neutropenia, thrombocytopenia, or agranulocytosis. - Kidney impairment: interstitial nephritis or renal function decline.

When prescribing Mesalazine, clinicians should consider several safety measures.

Dose adjustment: consider renal or hepatic impairment when prescribing. Monitoring: regular blood counts and renal function tests are recommended. Pregnancy: use only if potential benefit justifies risk, as safety data are limited. Drug interactions: review concomitant medications for potential interactions. Avoid in patients with known hypersensitivity to mesalazine or salicylates. Store at ambient temperature: keep in original container, protect from moisture and light.

Mesalazine can interact with other medicines; awareness of interaction severity guides management.

Major Interactions (Avoid): - Azathioprine: increased risk of bone marrow suppression. - Methotrexate: additive toxicity to liver and bone marrow. - Live vaccines: may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely): - Warfarin: possible enhancement of anticoagulant effect. - Oral contraceptives: may reduce efficacy of contraceptive hormones. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): increased gastrointestinal irritation.