GNH USA

Europe — EMA

Mesalazina Dorom

GNH USA supplies Mesalazina Dorom (Mesalazine), a aminosalicylate for ulcerative colitis treatment and maintenance of remission. Request a quote for supply.

Mesalazine

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1
Pack/s

What is Mesalazine?

Mesalazine, the active ingredient in Mesalazina Dorom, is an aminosalicylate presented as an oral tablet for oral use. It is used to treat ulcerative colitis and to maintain remission in patients with this condition.

GNH USA supplies Mesalazina Dorom as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Mesalazine used for?

Mesalazina Dorom is an aminosalicylate indicated for inflammatory bowel disease management.

Ulcerative colitis: induction of remission in active disease Maintenance of remission in ulcerative colitis: helps sustain disease control

What are the side effects of Mesalazine?

Mesalazina Dorom may cause a range of adverse reactions.

Common Side Effects: - Nausea - Abdominal pain or cramps - Headache - Flatulence or bloating - Rash or mild skin irritation - Vomiting

Serious or Rare Side Effects: - Myocarditis or pericarditis - Severe allergic reactions (anaphylaxis, angioedema) - Blood dyscrasias such as neutropenia or agranulocytosis - Acute pancreatitis - Toxic colitis or severe colitis flare - Hepatic dysfunction

What precautions apply to Mesalazine?

Before initiating therapy, several safety considerations should be observed.

Monitor renal function: assess creatinine and eGFR regularly Monitor hepatic function: check liver enzymes periodically Assess disease activity: ensure appropriate disease severity before use Avoid in patients with known hypersensitivity to mesalazine or other aminosalicylates Use caution during pregnancy and lactation: benefits must outweigh potential risks Store at room temperature: keep in the original container, protect from moisture and direct sunlight

What does Mesalazine interact with?

Mesalazina Dorom can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Azathioprine or 6‑mercaptopurine: increased risk of bone‑marrow suppression - Warfarin: potential enhancement of anticoagulant effect - Live vaccines: may reduce vaccine efficacy or increase infection risk

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase renal toxicity - Oral contraceptives: possible reduction in contraceptive effectiveness

Frequently asked questions

What is Mesalazina Dorom used for?+
Mesalazina Dorom contains mesalazine, an aminosalicylate prescribed to induce remission in active ulcerative colitis and to maintain remission in patients whose disease is already under control. It works locally in the colon to reduce inflammation.
How does mesalazine work in ulcerative colitis?+
Mesalazine inhibits the cyclooxygenase and lipoxygenase pathways in the intestinal lining, decreasing the production of prostaglandins and leukotrienes. This reduction in inflammatory mediators lessens mucosal irritation and promotes healing of the colon.
What is the usual dose of Mesalazina Dorom?+
The dosage of Mesalazina Dorom is individualized by the prescribing clinician based on disease severity, patient weight, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Mesalazina Dorom safe during pregnancy or breastfeeding?+
Safety data for mesalazine in pregnancy and lactation are limited. The prescriber must weigh potential benefits against possible risks. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.
How do I order Mesalazina Dorom from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Mesalazina Dorom compare with other ulcerative colitis treatments?+
Mesalazina Dorom belongs to the aminosalicylate class, offering a locally acting anti‑inflammatory option. Compared with systemic steroids or immunomodulators, it has a more favorable safety profile for long‑term maintenance but may be less potent for severe flares, where combination therapy might be required.
What are the storage and handling requirements for Mesalazina Dorom?+
Store Mesalazina Dorom at room temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and discard any product that appears discoloured or damaged.
How is Mesalazina Dorom administered?+
Mesalazina Dorom is taken orally, usually with water. The tablets can be swallowed whole or, if recommended by the prescriber, divided or crushed to aid swallowing, but patients should follow the specific instructions given by their healthcare professional.
What are the most serious risks associated with Mesalazina Dorom?+
Serious adverse events, though rare, include myocarditis, pericarditis, severe allergic reactions, blood dyscrasias such as neutropenia, and toxic colitis. Patients should seek immediate medical attention if they experience chest pain, severe rash, fever, or unexplained bleeding.
Who should not use Mesalazina Dorom?+
Individuals with known hypersensitivity to mesalazine, other aminosalicylates, or any component of the formulation should avoid this medication. It is also contraindicated in patients with severe renal or hepatic impairment unless closely monitored by a specialist.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Mesalazine
Route
Gastroenteral Use
Manufacturer
Teva Italia S.R.L.
Origin
EU

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