GNH USA

Europe — EMA

Meriofert Set

GNH USA supplies Meriofert Set (Follicle-Stimulating Hormone/Luteinising Hormone), a fertility agent for anovulatory infertility and controlled ovarian

Follicle-Stimulating Hormone, Luteinising Hormone

Request sourcing

1
Pack/s

What is Follicle-Stimulating Hormone, Luteinising Hormone?

Follicle-Stimulating Hormone and Luteinising Hormone, the active ingredients in Meriofert Set, are gonadotropins presented as a sterile injectable solution for subcutaneous use. They stimulate ovarian follicular development, estradiol production, and ovulation in women experiencing anovulatory infertility. These hormones are essential components of assisted reproductive protocols and are administered under specialist supervision.

GNH USA supplies Meriofert Set as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

What is Follicle-Stimulating Hormone, Luteinising Hormone used for?

Meriofert Set, a gonadotropin preparation, is used in fertility treatment pathways to induce and support ovarian follicle development. - Anovulatory infertility: promotes follicular growth and induces ovulation in women who do not ovulate spontaneously. - Assisted reproductive technology cycles: enables controlled ovarian hyperstimulation for in‑vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI). - Polycystic ovary syndrome (PCOS): facilitates regular ovulation when standard ovulation induction fails. - Hypogonadotropic hypogonadism: supplies exogenous gonadotropins to support follicular development in patients with deficient endogenous FSH/LH.

What are the side effects of Follicle-Stimulating Hormone, Luteinising Hormone?

Adverse reactions to Meriofert Set may vary in frequency and severity.

Common Side Effects: - Injection site pain, erythema, or swelling at the subcutaneous injection site. - Abdominal bloating, mild discomfort, or pelvic pressure during follicular development. - Nausea, headache, or transient fatigue reported after dosing. - Mild transient increase in estradiol levels causing temporary tenderness.

Serious or Rare Side Effects: - Severe ovarian hyperstimulation syndrome, which may cause ascites, thrombosis, or renal impairment. - Multiple pregnancy (twins or higher-order) resulting from excessive follicular response. - Allergic reaction or anaphylaxis presenting with rash, swelling, or respiratory distress.

What precautions apply to Follicle-Stimulating Hormone, Luteinising Hormone?

When using Meriofert Set, careful monitoring and patient assessment are essential. - Assess ovarian response with ultrasound before each dose. - Monitor serum estradiol levels during stimulation cycles. - Avoid use in patients with uncontrolled thyroid or adrenal disorders. - Use caution in individuals with a history of thromboembolic events. - Discontinue if signs of severe ovarian hyperstimulation appear. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Follicle-Stimulating Hormone, Luteinising Hormone interact with?

Meriofert Set may interact with other medications; awareness of major and moderate interactions helps ensure safety.

Major Interactions (Avoid): - Concomitant hCG administration may markedly increase risk of ovarian hyperstimulation syndrome. - Use with estrogen‑containing contraceptives can blunt the ovarian response. - Co‑administration with dopamine agonists may reduce gonadotropin efficacy.

Moderate Interactions (Monitor Closely): - Anticoagulant therapy may increase bleeding risk at injection sites. - Simultaneous use of other fertility drugs can amplify ovarian response, requiring dose adjustment. - Thyroid hormone replacement may affect ovarian sensitivity and should be monitored.

Frequently asked questions

What is Meriofert Set used for?+
Meriofert Set is a gonadotropin preparation used to treat infertility caused by anovulation and to support controlled ovarian stimulation in assisted reproductive technology cycles such as IVF or ICSI. It provides the necessary FSH and LH activity to promote follicular growth and ovulation under specialist supervision.
How does Follicle‑Stimulating Hormone and Luteinising Hormone work?+
The FSH component binds to FSH receptors on ovarian granulosa cells, stimulating their proliferation and estradiol production. The LH component activates LH receptors on theca cells, leading to androgen synthesis that is converted to estrogen. Together they drive follicular maturation, estradiol rise, and the final ovulatory trigger.
What is the usual dose of Meriofert Set?+
The dose of Meriofert Set is individualized. A qualified prescriber determines the amount, frequency, and duration based on the patient’s ovarian response, underlying condition, and treatment protocol. Exact dosing regimens are not standardized and must be set by the treating fertility specialist.
Is Meriofert Set safe during pregnancy or breastfeeding?+
Meriofert Set is intended for use before conception to induce ovulation. It is not indicated for use during an established pregnancy, and safety data for breastfeeding are lacking. Women who become pregnant should discontinue the product and receive appropriate obstetric care.
How do I order Meriofert Set from GNH USA?+
To place an order, submit an enquiry on the Meriofert Set product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed), and the necessary import documentation.
How does Meriofert Set compare with other gonadotropin products?+
Meriofert Set contains both FSH and LH in a single formulation, similar to other combined preparations such as Menopur (human menopausal gonadotropin). Compared with recombinant FSH alone, the added LH activity may benefit patients with specific ovarian response profiles, but the choice depends on individual clinical assessment and protocol preferences.
What are the storage and handling requirements for Meriofert Set?+
Meriofert Set must be stored at 2‑8 °C (refrigerated). Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking. Do not use the product if it has been exposed to temperatures outside this range or shows visible particles.
How is Meriofert Set administered?+
The product is supplied as a sterile lyophilised powder that is reconstituted with the appropriate diluent. It is then administered by subcutaneous injection, typically by a trained healthcare professional, according to the dosing schedule prescribed for the individual treatment cycle.
What are the most serious risks associated with Meriofert Set?+
The most serious risks include severe ovarian hyperstimulation syndrome (OHSS), which can lead to fluid accumulation, thrombosis, or renal impairment, as well as the possibility of multiple pregnancy and rare allergic reactions such as anaphylaxis. Patients are closely monitored to detect these complications early.
Who should not use Meriofert Set?+
Meriofert Set should not be used in individuals with known hypersensitivity to any of its components, in women who are already pregnant, or in patients with uncontrolled endocrine disorders such as untreated thyroid disease. Caution is also advised for those with a history of thromboembolic events or severe ovarian cysts.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Follicle-Stimulating Hormone, Luteinising Hormone
Route
Subcutaneous Use
Manufacturer
Ibsa Farmaceutici Italia
Origin
EU

Related products