GNH USA

Europe — EMA

Mercilon

GNH USA supplies Mercilon (Desogestrel/Ethinylestradiol), a combined oral contraceptive for prevention of pregnancy. Request a quote for global supply.

Desogestrel, Ethinylestradiol

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Pack/s

What is Desogestrel, Ethinylestradiol?

Desogestrel, the active ingredient in Mercilon, is a combined oral contraceptive presented as an oral tablet for oral use. Together with ethinylestradiol, it works to prevent pregnancy in women of reproductive age by inhibiting ovulation and altering cervical mucus. GNH USA supplies Mercilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

What is Desogestrel, Ethinylestradiol used for?

Mercilon, a combined oral contraceptive, is indicated for hormonal contraception in women. - Prevention of pregnancy: provides reliable contraceptive protection when taken daily as directed. - Regulation of menstrual cycles: helps establish regular withdrawal bleeding and reduces cycle variability. - Treatment of acne: reduces acne lesions by decreasing androgenic activity on the skin. - Relief of premenstrual symptoms: lessens bloating, breast tenderness, and mood changes associated with PMS.

What are the side effects of Desogestrel, Ethinylestradiol?

Like other combined oral contraceptives, Mercilon may be associated with a range of adverse reactions. Common Side Effects: - Nausea: mild to moderate stomach upset, especially during the first cycles. - Headache: tension‑type or migraine‑like headaches. - Breast tenderness: temporary swelling or soreness of the breasts. - Breakthrough bleeding: spotting or unscheduled bleeding between periods. Serious or Rare Side Effects: - Venous thromboembolism: blood clots in deep veins or lungs, requiring immediate medical attention. - Hypertension: significant increase in blood pressure that may need treatment. - Hepatic adenoma: rare benign liver tumor associated with long‑term estrogen exposure.

What precautions apply to Desogestrel, Ethinylestradiol?

Before prescribing Mercilon, clinicians should evaluate several safety considerations. - Smoking status: avoid use in women over 35 who smoke due to increased thrombotic risk. - Cardiovascular history: contraindicated in patients with hypertension, coronary artery disease, or stroke. - History of thromboembolism: not recommended for women with prior deep‑vein thrombosis or pulmonary embolism. - Liver disease: use with caution in active liver disease or hepatic tumors. - Migraine with aura: contraindicated in women experiencing migraine with visual disturbances. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

What does Desogestrel, Ethinylestradiol interact with?

Mercilon can interact with several medicines, altering its efficacy or safety profile. Major Interactions (Avoid): - Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin, rifampicin): markedly reduce contraceptive hormone levels, risking breakthrough bleeding. - Antiretroviral protease inhibitors (e.g., ritonavir): may increase hormone concentrations, raising thrombotic risk. - St. John’s wort: herbal inducer that decreases plasma levels of ethinylestradiol and desogestrel. Moderate Interactions (Monitor Closely): - Antibiotics (e.g., tetracycline, metronidazole): may slightly diminish contraceptive effect; advise backup method. - Diuretics (e.g., thiazides): can increase blood pressure; monitor cardiovascular status. - Antifungal azoles (e.g., ketoconazole): may increase hormone levels; watch for signs of estrogen excess.

Frequently asked questions

What is Mercilon used for?+
Mercilon is a combined oral contraceptive indicated for the prevention of pregnancy in women of reproductive age. It is also prescribed to help regulate menstrual cycles, reduce menstrual‑related symptoms, and treat acne associated with hormonal imbalance.
How does desogestrel and ethinylestradiol work in Mercilon?+
Desogestrel acts as a progestogen, suppressing the mid‑cycle luteinizing hormone surge and thereby preventing ovulation. Ethinylestradiol, a synthetic estrogen, stabilizes the endometrial lining and enhances negative feedback on gonadotropins, while both agents thicken cervical mucus and alter the uterine environment to reduce the chance of implantation.
What is the usual dose of Mercilon?+
The dosing regimen for Mercilon is determined by the prescribing healthcare professional. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and any missed‑dose instructions should be provided by the prescriber.
Is Mercilon safe to use during pregnancy or breastfeeding?+
Mercilon is not intended for use during pregnancy; it is a contraceptive meant to prevent pregnancy. If pregnancy occurs, the product should be discontinued and medical advice sought. Use during breastfeeding should be discussed with a healthcare provider, as hormonal contraceptives may affect milk production in some women.
How do I order Mercilon from GNH USA?+
To order Mercilon, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams across international markets, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Mercilon compare with other combined oral contraceptives?+
Mercilon contains desogestrel, a third‑generation progestogen, which is associated with a lower incidence of androgenic side effects such as acne compared with some older progestins. Its estrogen component, ethinylestradiol, is at a standard dose for combined pills, offering comparable contraceptive efficacy while differing slightly in bleeding pattern and tolerability.
How should Mercilon be stored and handled?+
Mercilon tablets should be stored at ambient temperature, below 25 °C (77 °F). Keep them in the original blister pack, protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability throughout its shelf life.
How is Mercilon administered?+
Mercilon is taken orally, usually as one tablet each day. The tablet should be swallowed with water, preferably at the same time each day, and can be taken with or without food. Consistent daily intake is essential for maintaining contraceptive effectiveness.
What are the most serious risks associated with Mercilon?+
The most serious risks include venous thromboembolism (blood clots), arterial thrombosis leading to heart attack or stroke, and hypertension. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should avoid using Mercilon and discuss alternatives with their clinician.
Who should not use Mercilon?+
Mercilon is contraindicated in women who are pregnant, have known or suspected breast cancer, have a history of thromboembolic events, uncontrolled hypertension, severe liver disease, or who are smokers over the age of 35. It should also be avoided in individuals with migraine with aura or known hypersensitivity to any component of the tablet.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Desogestrel, Ethinylestradiol
Route
Oral Use
Manufacturer
Organon Pharma (Uk) Limited
Origin
EU

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