GNH USA

Europe — EMA

Mercilon

GNH USA supplies Mercilon (desogestrel/ethinylestradiol), a combined oral contraceptive for prevention of pregnancy. Request a quote for global supply.

Desogestrel, Ethinylestradiol

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What is Desogestrel, Ethinylestradiol?

Desogestrel and ethinylestradiol, the active ingredients in Mercilon, are a combined oral contraceptive presented as a 150 µg desogestrel / 20 µg ethinylestradiol tablet for oral use. It prevents pregnancy in women of reproductive age.

GNH USA supplies Mercilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Mercilon is marketed across the European Union and complies with EU pharmacovigilance regulations. This ensures consistent potency and safety for patients.

What is Desogestrel, Ethinylestradiol used for?

Mercilon, a combined oral contraceptive, acts on the hormonal regulation pathway to prevent pregnancy.

Prevention of pregnancy: provides reliable contraceptive protection for women of childbearing potential. Regulation of menstrual cycles: helps achieve more predictable and lighter menstrual bleeding. Management of acne: can improve acne symptoms by reducing androgenic activity. Reduction of dysmenorrhea: alleviates painful menstrual cramps. Treatment of endometriosis‑associated pain: may reduce pelvic pain symptoms.

What are the side effects of Desogestrel, Ethinylestradiol?

Mercilon may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Nausea: mild stomach upset, especially during the first cycles. - Headache: transient tension‑type headaches. - Breast tenderness: temporary swelling or discomfort. - Spotting or breakthrough bleeding: irregular bleeding between periods.

Serious or Rare Side Effects: - Venous thromboembolism: deep vein thrombosis or pulmonary embolism, potentially life‑threatening. - Stroke or myocardial infarction: rare cerebrovascular or cardiac events, more likely in smokers or high‑risk women. - Severe allergic reaction: anaphylaxis or angioedema requiring immediate medical attention.

What precautions apply to Desogestrel, Ethinylestradiol?

Before prescribing Mercilon, clinicians should evaluate several safety considerations. - Contraindications: known thrombosis, estrogen‑dependent tumor, pregnancy, or breastfeeding. - Smoking: avoid use in women over 35 who smoke due to increased cardiovascular risk. - Cardiovascular risk: assess history of hypertension, heart disease, or hyperlipidaemia. - Drug interactions: review concomitant medications that induce hepatic enzymes or affect coagulation. - Regular monitoring: check blood pressure and lipid profile periodically during therapy. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and light.

What does Desogestrel, Ethinylestradiol interact with?

Mercilon can interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid): - Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may markedly reduce contraceptive efficacy. - Rifampicin or other strong CYP3A4 inducers: can decrease hormone levels, increasing risk of unintended pregnancy.

Moderate Interactions (Monitor Closely): - Antifungal agents (ketoconazole, itraconazole): may increase hormone concentrations, raising risk of side effects. - St. John’s wort: may lower hormone levels, potentially reducing contraceptive reliability. - HIV protease inhibitors (ritonavir): can affect hormone metabolism, requiring clinical monitoring.

Frequently asked questions

What is Mercilon used for?+
Mercilon is a combined oral contraceptive indicated for the prevention of pregnancy in women of reproductive age. By delivering a fixed dose of desogestrel and ethinylestradiol daily, it provides reliable contraceptive protection when taken as prescribed.
How does desogestrel/ethinylestradiol work?+
Desogestrel acts as a progestin, binding to progesterone receptors, while ethinylestradiol is a synthetic estrogen that activates estrogen receptors. Together they suppress the mid‑cycle LH and FSH surge, preventing ovulation, and also thicken cervical mucus and alter the endometrium, creating conditions unfavorable for fertilisation and implantation.
What is the usual dose of Mercilon?+
The dosing regimen for Mercilon is determined by the prescribing healthcare professional. Typically, the product is taken as one tablet daily at the same time each day, but the exact schedule and any missed‑dose instructions are provided by the prescriber.
Is Mercilon safe during pregnancy or breastfeeding?+
Mercilon is classified as Pregnancy Category X, meaning it is contraindicated in pregnancy because it may cause harm to the fetus. It is also not recommended for breastfeeding women, as hormonal exposure could affect milk production and infant health.
How do I order Mercilon from GNH USA?+
To order Mercilon, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any necessary import documentation.
How does Mercilon compare with other combined oral contraceptives?+
Mercilon contains desogestrel, a third‑generation progestin, combined with ethinylestradiol. Compared with older formulations that use levonorgestrel, desogestrel is associated with a lower incidence of androgenic side effects such as acne, while maintaining similar contraceptive efficacy. However, all combined oral contraceptives share similar risks for thromboembolic events.
How should Mercilon be stored and handled?+
Mercilon tablets should be stored at ambient temperature, below 25 °C, in their original blister pack. Protect them from moisture, direct sunlight, and excessive heat. Keep the product out of reach of children and do not use tablets that appear discoloured or damaged.
How is Mercilon administered?+
Mercilon is taken orally, usually as a single tablet each day. It should be swallowed with water, preferably at the same time each day, and can be taken with or without food. Consistent daily intake helps maintain steady hormone levels and maximises contraceptive effectiveness.
What are the most serious risks associated with Mercilon?+
The most serious risks include venous thromboembolism (deep‑vein thrombosis or pulmonary embolism), arterial events such as stroke or myocardial infarction, and severe allergic reactions like anaphylaxis. These events are rare but require immediate medical attention if symptoms arise.
Who should not use Mercilon?+
Mercilon should not be used by women with a history of thromboembolic disorders, estrogen‑dependent tumors, active liver disease, known or suspected pregnancy, or those who are breastfeeding. It is also contraindicated in smokers over 35 years of age and in individuals with uncontrolled hypertension or certain cardiovascular conditions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Desogestrel, Ethinylestradiol
Route
Oral Use
Manufacturer
Organon Italia S.R.L.
Origin
EU

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