Mercilon

Desogestrel / Ethinylestradiol, the active ingredient in Mercilon, is a combined oral contraceptive presented as a 0.15 mg desogestrel / 0.02 mg ethinylestradiol tablet for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation, thickening cervical mucus, and altering the endometrial lining.

GNH USA supplies Mercilon as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance for the EU market.

Mercilon, a combined oral contraceptive, is used to prevent pregnancy by modulating the hormonal regulation of the menstrual cycle.

Contraception: provides reliable prevention of unintended pregnancy when taken as directed. Family planning: enables women to plan and space pregnancies for optimal reproductive health. Menstrual cycle control: may help achieve more regular menstrual bleeding patterns.

Common Side Effects: - Nausea: mild to moderate stomach upset, especially during the first cycles. - Breast tenderness: transient swelling or discomfort of the breasts. - Headache: occasional tension‑type or migraine‑like headaches. - Irregular bleeding: spotting or breakthrough bleeding between periods. - Mood changes: mild fluctuations in mood or emotional state.

Serious or Rare Side Effects: - Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism, requiring immediate medical attention. - Arterial thrombosis: increased risk of stroke or myocardial infarction, particularly in smokers over 35. - Severe allergic reaction: rash, swelling, or anaphylaxis. - Liver dysfunction: jaundice or abnormal liver enzyme levels. - Hypertension: sudden rise in blood pressure.

Precautions should be observed when prescribing Mercilon to ensure safety and effectiveness. - Smoking: avoid smoking, especially in women over 35, due to heightened thrombotic risk. - Cardiovascular disease: contraindicated in patients with a history of thromboembolism, myocardial infarction, or stroke. - Migraine with aura: use with caution as it may increase stroke risk. - Liver disease: monitor hepatic function and adjust use in severe impairment. - Pregnancy: contraindicated; product is classified as pregnancy category X. - Store at ambient temperature: keep below 25 °C, retain in the original packaging, and protect from moisture and light.

Drug interactions may alter the efficacy or safety profile of Mercilon. Major Interactions (Avoid): - Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): may markedly reduce contraceptive effectiveness. - Rifampin: decreases hormone levels, increasing the risk of unintended pregnancy. - Griseofulvin: can lower oral contraceptive efficacy. Moderate Interactions (Monitor Closely): - Azole antifungals (e.g., ketoconazole): may increase hormone concentrations, raising side‑effect potential. - St. John’s wort: may reduce contraceptive effectiveness through enzyme induction. - Protease inhibitors: can alter hormone metabolism, requiring clinical monitoring.