GNH USA

Europe — EMA

Mercalm

GNH USA supplies Mercalm (Dimenhydrinate), an antihistamine for motion sickness, postoperative nausea and vertigo. Request a quote for global supply.

Dimenhydrinate, Caffeine

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1
Pack/s

What is Dimenhydrinate, Caffeine?

Dimenhydrinate, the active ingredient in Mercalm, is an antihistamine presented as a tablet for oral use. It treats motion‑induced nausea, vomiting and vertigo in adults and children. GNH USA supplies Mercalm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Dimenhydrinate, Caffeine used for?

Dimenhydrinate, combined with caffeine, acts on the vestibular system and histamine pathways to control nausea and related symptoms.

- Motion Sickness: reduces vertigo, nausea and vomiting associated with travel. - Post‑operative Nausea: helps control nausea and vomiting after surgical procedures. - Vertigo: alleviates dizziness caused by vestibular disturbances.

What are the side effects of Dimenhydrinate, Caffeine?

Common Side Effects: - Drowsiness: mild sedation or fatigue. - Dry Mouth: reduced salivation leading to throat discomfort. - Blurred Vision: temporary visual disturbances. - Constipation: slowed gastrointestinal motility. - Headache: mild to moderate head pain. - Increased Heart Rate: mild tachycardia.

Serious or Rare Side Effects: - Allergic Reactions: rash, swelling, or urticaria. - Cardiac Arrhythmia: irregular heart rhythms. - Seizures: rare convulsive episodes. - Severe Hypotension: marked drop in blood pressure. - Confusion or Hallucinations: altered mental status. - Respiratory Depression: difficulty breathing in severe cases.

What precautions apply to Dimenhydrinate, Caffeine?

Before using Mercalm, consider the following precautions: - Glaucoma: avoid if you have narrow‑angle glaucoma. - Urinary Retention: use cautiously in patients with prostate enlargement. - Asthma: monitor for bronchospasm. - Pregnancy: consult a healthcare professional before use. - Elderly: start with the lowest effective dose. - Drug Interactions: review concomitant medications. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

What does Dimenhydrinate, Caffeine interact with?

Dimenhydrinate may interact with several drug classes.

Major Interactions (Avoid): - MAO Inhibitors: risk of hypertensive crisis. - CNS Depressants: additive sedation. - Anticholinergic Drugs: excessive anticholinergic load. - Alcohol: enhanced drowsiness. - Certain Antidepressants: increased anticholinergic effects.

Moderate Interactions (Monitor Closely): - Antihypertensives: possible additive blood pressure lowering. - Diuretics: may enhance dehydration. - Other Antihistamines: increased sedation. - CYP1A2 Inhibitors (e.g., ciprofloxacin): elevated caffeine levels. - Antacids: may affect absorption.

Frequently asked questions

What is Mercalm used for?+
Mercalm is an oral anti‑emetic medication that combines dimenhydrinate and caffeine to treat motion‑induced nausea, vomiting, postoperative nausea, and vertigo. It is commonly prescribed for travelers, surgical patients, and individuals experiencing vestibular disturbances.
How does dimenhydrinate work?+
Dimenhydrinate works by blocking H1 histamine receptors and exerting anticholinergic activity, which reduces stimulation of the vestibular system that triggers nausea. This dual action helps control vomiting and dizziness associated with motion or vestibular disorders.
What is the usual dose of Mercalm?+
The dosage of Mercalm is determined by the prescribing healthcare professional based on the patient’s age, weight, condition severity, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Mercalm safe during pregnancy or breastfeeding?+
Pregnancy and breastfeeding safety should be evaluated by a qualified healthcare provider. Dimenhydrinate is classified as Category B in many regions, indicating no proven risk in animal studies, but human data are limited. Caffeine exposure should also be considered.
How do I order Mercalm from GNH USA?+
To order Mercalm, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.
How does Mercalm compare with other anti‑emetics?+
Compared with other antihistamine anti‑emetics such as meclizine, Mercalm adds caffeine, which can reduce drowsiness and improve alertness. It offers a broader symptom control for motion sickness but may have a higher incidence of stimulant‑related side effects.
What are the storage and handling requirements for Mercalm?+
Mercalm should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use if the packaging is damaged.
How is Mercalm administered?+
Mercalm is taken orally, usually with a glass of water. The tablet should be swallowed whole and not chewed or crushed unless directed by a healthcare professional. It can be taken with or without food, depending on tolerability.
What are the most serious risks associated with Mercalm?+
Serious risks include severe allergic reactions (rash, swelling, difficulty breathing), cardiac arrhythmias, seizures, and marked hypotension. Patients should seek immediate medical attention if they experience any of these symptoms.
Who should not use Mercalm?+
Mercalm should be avoided in individuals with known hypersensitivity to dimenhydrinate, caffeine, or any excipients, as well as patients with narrow‑angle glaucoma, severe urinary retention, uncontrolled asthma, or those taking MAO inhibitors.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dimenhydrinate, Caffeine
Route
Oral Use
Manufacturer
Melisana Pharma
Origin
EU

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