GNH USA

Europe — EMA

Meralys Ha

GNH USA supplies Meralys Ha (Xylometazoline), a nasal decongestant for congestion due to common cold and allergic rhinitis. Request a quote for global supply.

Xylometazoline Hydrochloride

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What is Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride, the active ingredient in Meralys Ha, is an alpha‑adrenergic agonist presented as a nasal spray for intranasal use. It relieves nasal congestion associated with the common cold and allergic rhinitis by reducing swelling of the nasal mucosa in the nasal passages and improves airflow.

GNH USA supplies Meralys Ha as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures product quality through rigorous testing and adheres to global regulatory standards. Delivery is coordinated across multiple regions to meet local market requirements.

What is Xylometazoline Hydrochloride used for?

Xylometazoline, an alpha‑adrenergic agonist nasal decongestant, acts on the nasal mucosal vasculature to relieve congestion.

- Common cold: reduces nasal blockage, eases breathing, and helps restore normal airflow during viral upper respiratory infection. - Allergic rhinitis: alleviates swelling of the nasal mucosa, diminishes congestion, and improves nasal patency in response to allergen exposure. - Environmental irritants: provides temporary relief of nasal congestion caused by exposure to smoke, dust, or pollutants. - Post‑nasal surgery swelling: helps reduce mild congestion and improves breathing after nasal surgical procedures.

What are the side effects of Xylometazoline Hydrochloride?

Xylometazoline may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nasal irritation: mild burning or stinging sensation in the nostrils. - Dryness: reduced moisture leading to a dry nose. - Sneezing: transient increase in sneezing episodes. - Headache: mild headache following application.

Serious or Rare Side Effects: - Hypertension: significant rise in blood pressure, especially with overuse. - Rebound congestion: worsening nasal blockage after prolonged use (>3 days). - Cardiac arrhythmia: irregular heart rhythm in susceptible individuals. - Severe allergic reaction: rare anaphylaxis with swelling, rash, or difficulty breathing.

What precautions apply to Xylometazoline Hydrochloride?

Before using Xylometazoline nasal spray, consider the following precautions to ensure safe and effective treatment. - Duration of use: limit application to no more than three consecutive days to avoid rebound congestion. - Cardiovascular conditions: avoid use in patients with uncontrolled hypertension or severe heart disease. - Glaucoma: contraindicated in individuals with narrow‑angle glaucoma. - Pregnancy and lactation: safety not established; use only if clearly needed after professional assessment. - Drug interactions: do not combine with other topical decongestants or systemic vasoconstrictors without medical guidance. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Xylometazoline Hydrochloride interact with?

Xylometazoline can interact with certain medicines, altering its effects or increasing the risk of adverse events.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): concurrent use may cause hypertensive crisis. - Other nasal decongestants: combined vasoconstriction can lead to excessive blood pressure rise. - Systemic sympathomimetics: may amplify cardiovascular stimulation.

Moderate Interactions (Monitor Closely): - Antihypertensive agents: nasal spray may reduce the effectiveness of blood pressure medications. - Beta‑blockers: possible additive effects on heart rate and blood pressure. - Antidepressants (e.g., tricyclics): may increase risk of cardiovascular side effects.

Frequently asked questions

What is Meralys Ha used for?+
Meralys Ha is a nasal spray containing Xylometazoline Hydrochloride, an over‑the‑counter nasal decongestant. It is indicated for the temporary relief of nasal congestion caused by the common cold and allergic rhinitis, helping to open the nasal passages and improve breathing.
How does Xylometazoline work?+
Xylometazoline acts as a selective alpha‑adrenergic receptor agonist on the smooth muscle of nasal blood vessels. By stimulating α1 receptors, it causes vasoconstriction, which reduces blood flow and swelling in the nasal mucosa, thereby decreasing congestion and restoring airflow.
What is the usual dose of Meralys Ha?+
The specific dosing regimen for Meralys Ha is determined by a healthcare professional. Typically, a few sprays into each nostril are used no more than three consecutive days, but the prescriber sets the exact amount and frequency based on the individual’s condition.
Is Meralys Ha safe during pregnancy or breastfeeding?+
Safety data for Xylometazoline in pregnancy and lactation are limited. It should only be used if clearly needed and after a risk‑benefit assessment by a qualified healthcare provider. Women who are pregnant or nursing should consult their physician before using the product.
How do I order Meralys Ha from GNH USA?+
To place an order, submit an enquiry on the Meralys Ha product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Meralys Ha compare with other nasal decongestants?+
Meralys Ha contains Xylometazoline, a selective alpha‑adrenergic agonist, which provides rapid decongestion with minimal systemic absorption. Compared with older agents such as phenylephrine, Xylometazoline often offers longer duration of action and a lower incidence of systemic side effects, though all decongestants share a risk of rebound congestion with overuse.
What are the storage requirements for Meralys Ha?+
Store Meralys Ha at room temperature, preferably below 25 °C. Keep the spray bottle in its original packaging, protect it from moisture, direct sunlight and extreme heat. Do not freeze the product, and ensure the cap is tightly closed when not in use.
How is Meralys Ha administered?+
Meralys Ha is applied intranasally. The user gently inserts the spray tip into each nostril and delivers the prescribed number of sprays, usually one to two per nostril, while keeping the head upright. The spray should be used only as directed by a healthcare professional.
What are the most serious risks associated with Meralys Ha?+
Serious risks include hypertension, especially if used excessively or in patients with pre‑existing cardiovascular disease, and rebound nasal congestion after prolonged use beyond three days. Rarely, severe allergic reactions such as anaphylaxis may occur, requiring immediate medical attention.
Who should not use Meralys Ha?+
Meralys Ha should be avoided by individuals with uncontrolled hypertension, severe heart disease, narrow‑angle glaucoma, or known hypersensitivity to Xylometazoline or any component of the formulation. Children under the age specified on the product label and patients using other nasal decongestants simultaneously should also refrain from use unless advised by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Xylometazoline Hydrochloride
Route
Nasal Use
Manufacturer
Jadran-Galenski Laboratorij D.D.
Origin
EU

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