GNH USA

Europe — EMA

Meralys 1 Mg/Ml

GNH USA supplies Meralys 1 Mg/mL (Xylometazoline Hydrochloride), a nasal decongestant for relief of congestion due to the common cold, sinusitis and allergic

Xylometazoline Hydrochloride

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What is Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride, the active ingredient in Meralys 1 Mg/mL, is an imidazoline derivative presented as a 1 mg/mL nasal solution for nasal use. It relieves nasal congestion associated with the common cold, sinusitis and allergic rhinitis in adults and children.

GNH USA supplies Meralys 1 Mg/mL as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other healthcare facilities worldwide, with a focus on quality and regulatory compliance. The product meets EU pharmacopeial standards and is manufactured under GMP conditions.

What is Xylometazoline Hydrochloride used for?

Xylometazoline Hydrochloride is a topical nasal decongestant that reduces swelling of the nasal mucosa, improving airflow.

- Common cold: alleviates nasal congestion by constricting dilated blood vessels in the nasal mucosa, providing rapid relief of a blocked nose. - Sinusitis: decreases mucosal edema in the sinus passages, helping to restore normal breathing and drainage. - Allergic rhinitis: reduces congestion caused by allergic inflammation, improving nasal patency during exposure to allergens.

What are the side effects of Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride may cause local and systemic adverse reactions, most of which are mild and transient.

Common Side Effects: - Nasal irritation or burning sensation - Dryness of nasal mucosa - Sneezing - Headache - Epistaxis (nosebleeds)

Serious or Rare Side Effects: - Severe hypertension - Tachycardia or arrhythmia - Allergic reactions such as rash, itching or swelling - Rebound nasal congestion (rhinitis medicamentosa) with prolonged use - Nasal ulceration

What precautions apply to Xylometazoline Hydrochloride?

When using Meralys, consider the following precautions to ensure safe and effective treatment.

- Use in children under 2 years: not recommended - Pregnancy: consult a healthcare professional before use - Existing hypertension or cardiovascular disease: use with caution - Concurrent use of monoamine oxidase inhibitors (MAOIs): avoid due to additive sympathomimetic effects - Prolonged use beyond 3 days: risk of rebound congestion; limit duration - Store at room temperature: keep in original container, protect from light and moisture

What does Xylometazoline Hydrochloride interact with?

Xylometazoline Hydrochloride can interact with other medications, requiring attention to avoid adverse effects.

Major Interactions (Avoid): - Oral decongestants such as pseudoephedrine: additive sympathomimetic activity may raise blood pressure - Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis - Tricyclic antidepressants: may enhance cardiovascular stimulation

Moderate Interactions (Monitor Closely): - Beta‑blockers: may mask tachycardia induced by the nasal spray - Antihypertensive agents: possible reduction in blood pressure control - Other intranasal medications: increased local irritation when used together

Frequently asked questions

What is Meralys 1 Mg/mL used for?+
Meralys 1 Mg/mL contains Xylometazoline Hydrochloride and is indicated for the temporary relief of nasal congestion associated with the common cold, sinusitis and allergic rhinitis. It works by narrowing the blood vessels in the nasal passages, helping to open the airway.
How does Xylometazoline Hydrochloride work?+
Xylometazoline Hydrochloride is a topical alpha‑adrenergic agonist. By stimulating α‑adrenergic receptors on nasal blood vessels, it causes vasoconstriction, which reduces swelling of the nasal mucosa and improves airflow, thereby relieving congestion.
What is the usual dose of Meralys?+
The appropriate dose of Meralys is determined by a qualified healthcare professional. Typically, a few drops are administered into each nostril as directed, and the frequency should not exceed the label‑recommended maximum to avoid rebound congestion.
Is Meralys safe during pregnancy or breastfeeding?+
Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their physician, who can weigh potential benefits against any possible risks.
How do I order Meralys from GNH USA?+
To order Meralys, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Meralys compare with other nasal decongestants?+
Meralys contains Xylometazoline, an imidazoline‑type decongestant, which provides rapid onset of action similar to phenylephrine‑based sprays. Compared with oxymetazoline, it has a comparable efficacy profile but may differ slightly in duration of effect and tolerability, making choice dependent on individual response and physician preference.
How should Meralys be stored and handled?+
Store Meralys at room temperature, below 25 °C, in its original container. Protect the bottle from direct sunlight, moisture and extreme temperatures. Keep the cap tightly closed when not in use to maintain sterility.
How is Meralys administered?+
Meralys is applied as a nasal solution. The user tilts the head slightly forward, inserts the tip into a nostril, and delivers the prescribed number of drops. The same procedure is repeated for the other nostril if required.
What are the most serious risks associated with Meralys?+
Serious risks include severe hypertension, tachycardia or arrhythmias, allergic reactions, and rebound nasal congestion (rhinitis medicamentosa) if used for more than three consecutive days. Patients experiencing these symptoms should discontinue use and seek medical attention promptly.
Who should not use Meralys?+
Meralys should be avoided in children under two years of age, in individuals with known hypersensitivity to Xylometazoline or any formulation component, and in patients taking monoamine oxidase inhibitors. Those with uncontrolled hypertension or severe cardiovascular disease should consult a physician before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Xylometazoline Hydrochloride
Route
Nasal Use
Manufacturer
Jadran-Galenski Laboratorij D.D.
Origin
EU

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