GNH USA

Europe — EMA

Menopur

GNH USA supplies Menopur (Menotropin), a gonadotropin for infertility due to anovulation and controlled ovarian stimulation. Request a quote for supply.

Menotrophin

Request sourcing

1
Pack/s

What is Menotrophin?

Menotropin, the active ingredient in Menopur, is a gonadotropin presented as an injection solution for subcutaneous administration. It provides exogenous follicle‑stimulating hormone (FSH) and luteinizing hormone (LH) activity to stimulate ovarian follicular development and ovulation in women with infertility due to anovulation or undergoing assisted reproductive technology cycles.

GNH USA supplies Menopur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to this fertility therapy for qualified healthcare providers and patients through established distribution networks.

What is Menotrophin used for?

Menopur (menotropin) is used in fertility treatment to stimulate ovarian function. - Infertility due to anovulation: promotes follicular growth and ovulation to improve chances of conception. - Controlled ovarian stimulation in assisted reproductive technology (ART): supports multiple follicle development for IVF or ICSI cycles. - Ovarian stimulation for egg donation programs: enhances oocyte yield in donor cycles. - Luteal phase support in certain protocols: provides LH activity to aid corpus luteum function.

What are the side effects of Menotrophin?

Menopur may cause a range of adverse reactions, which are generally related to its hormonal activity and injection site. Common Side Effects: - Injection site pain: mild to moderate discomfort at the injection site. - Abdominal bloating: transient abdominal distension. - Nausea: occasional nausea. Serious or Rare Side Effects: - Ovarian hyperstimulation syndrome (severe): rapid weight gain, abdominal pain, shortness of breath. - Thromboembolic events: deep vein thrombosis or pulmonary embolism. - Allergic reaction: rash, urticaria, or anaphylaxis.

What precautions apply to Menotrophin?

Before using Menopur, consider the following precautions to minimize risks and ensure safe administration. - Assess ovarian reserve: evaluate baseline follicle count and hormone levels before initiating therapy. - Monitor for OHSS: regular ultrasound and estradiol monitoring to detect early signs of ovarian hyperstimulation syndrome. - Review medical history: contraindicate use in active malignancy, uncontrolled thyroid disease, or severe cardiovascular conditions. - Avoid concurrent gonadotropins: do not combine with other FSH or LH preparations without specialist guidance. - Pregnancy testing: confirm negative pregnancy test prior to starting treatment. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake the vial.

What does Menotrophin interact with?

Menopur can interact with other medicines or hormonal agents; awareness of these interactions helps prevent adverse outcomes. Major Interactions (Avoid): - GnRH antagonists: may blunt the intended ovarian response. - High‑dose estrogen therapy: can interfere with follicular development. - Anticoagulants: increased risk of bleeding from ovarian cyst rupture. Moderate Interactions (Monitor Closely): - Oral contraceptives: may require washout period before stimulation. - Thyroid hormone replacement: monitor thyroid function as gonadotropins can affect hormone levels. - Diuretics: may mask fluid shifts associated with OHSS.

Frequently asked questions

What is Menopur used for?+
Menopur is a gonadotropin preparation used in reproductive medicine to treat infertility caused by anovulation and to provide controlled ovarian stimulation during assisted reproductive technology procedures such as in‑vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI). It helps develop multiple mature follicles, increasing the number of retrievable oocytes for fertilisation.
How does menotropin work?+
Menotropin contains both follicle‑stimulating hormone (FSH) and luteinizing hormone (LH). After subcutaneous injection, FSH binds to receptors on granulosa cells, promoting follicle growth and estrogen synthesis, while LH activates receptors on theca cells and mature follicles, supporting androgen production and final oocyte maturation, together leading to ovulation.
What is the usual dose of Menopur?+
The specific dose of Menopur is individualized by the treating physician based on the patient’s ovarian reserve, treatment protocol and response to monitoring. The prescriber determines the number of international units (IU) per injection and the total duration of therapy, adjusting as needed throughout the stimulation cycle.
Is Menopur safe in pregnancy or breastfeeding?+
Menopur is intended for use before conception and is not administered during an established pregnancy. Its safety in pregnancy has not been established, and it is generally avoided once pregnancy is confirmed. Limited data are available for breastfeeding; therefore, use while nursing is not recommended without specialist advice.
How do I order Menopur from GNH USA?+
To order Menopur, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if required) and the necessary import documentation.
How does Menopur compare with the main alternative drug or class?+
The primary alternative to Menopur is recombinant FSH (rFSH) products such as follitropin alfa. Menotropin provides both FSH and LH activity in a single preparation, which can simplify dosing compared with separate recombinant FSH and LH agents. Recombinant products offer higher purity and batch‑to‑batch consistency, while Menotropin is derived from urinary sources and may be more cost‑effective in some markets.
How should Menopur be stored and handled?+
Menopur must be stored in a refrigerator at 2‑8 °C (36‑46 °F). Keep the vial in its original packaging, protect it from light, and do not freeze or shake the solution. Before use, allow the product to reach room temperature for a few minutes; avoid using any vial that appears cloudy or contains particles.
How is Menopur administered?+
Menopur is supplied as a sterile injection solution for subcutaneous administration. The prescribed dose is drawn into a sterile syringe and injected into the subcutaneous tissue of the abdomen or thigh, typically once daily or as directed by the fertility specialist. Injection technique and site rotation should follow standard clinical guidelines.
What are the most serious risks to watch for with Menopur?+
The most serious risks associated with Menopur include severe ovarian hyperstimulation syndrome (OHSS), which can cause rapid weight gain, abdominal pain, shortness of breath, and fluid accumulation; thromboembolic events such as deep‑vein thrombosis or pulmonary embolism; and rare allergic reactions that may progress to anaphylaxis. Prompt medical attention is required if any of these symptoms develop.
Who should not use Menopur?+
Menopur is contraindicated in women with active or uncontrolled ovarian or breast cancer, severe uncontrolled thyroid disease, uncontrolled hypertension, or significant cardiovascular disease. It should also be avoided in patients with known hypersensitivity to menotropin or any component of the formulation, and in women who are already pregnant.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Menotrophin
Route
Subcutaneous Use
Manufacturer
Ferring Gmbh
Origin
EU

Related products