Memantine Teva

Memantine, the active ingredient in Memantine Teva, is a NMDA receptor antagonist presented as an oral tablet for oral use. It is indicated for the treatment of moderate to severe Alzheimer's disease in adults.

GNH USA supplies Memantine Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Memantine acts on the glutamatergic system and is used in the management of Alzheimer's disease.

Alzheimer's disease (moderate to severe): helps maintain cognition and daily functional abilities. Alzheimer's disease (as part of combination therapy with cholinesterase inhibitors): may provide additional symptomatic benefit when used together with standard treatments.

Common Side Effects: - Dizziness - Headache - Constipation - Somnolence - Confusion - Fatigue

Serious or Rare Side Effects: - Seizures - Severe skin reactions (e.g., Stevens‑Johnson syndrome) - Cardiac arrhythmias - Hepatic dysfunction - Suicidal thoughts or behavior

Memantine should be used with caution in specific clinical situations. - Renal impairment: dose adjustment may be required and renal function should be monitored. - Hepatic impairment: monitor liver enzymes and consider dose modification. - History of seizures: observe for increased seizure frequency. - Concomitant use with other NMDA antagonists: avoid due to additive neuro‑protective effects. - Elderly patients: higher risk of confusion and falls; start at low dose. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Memantine may interact with several medicines that affect its excretion or central nervous system activity.

Major Interactions (Avoid): - Other NMDA antagonists (e.g., amantadine, dextromethorphan): may increase neuro‑toxic risk. - Strong renal tubular secretion inhibitors (e.g., cimetidine, trimethoprim): can raise memantine plasma levels.

Moderate Interactions (Monitor Closely): - Anticholinergic agents: may blunt cognitive benefits. - CNS depressants (e.g., benzodiazepines, opioids): may enhance sedation. - Diuretics: monitor electrolytes and renal function. - High‑dose vitamin D supplements: may affect calcium homeostasis.