GNH USA

Europe — EMA

Memantina Aurovitas

GNH USA supplies Memantina Aurovitas (Memantine Hydrochloride), a NMDA receptor antagonist for moderate to severe Alzheimer’s disease.

Memantine Hydrochloride

Request sourcing

1
Pack/s

What is Memantine Hydrochloride?

Memantine Hydrochloride, the active ingredient in Memantina Aurovitas, is a NMDA receptor antagonist presented as an oral tablet for oral use. It is indicated for the treatment of moderate to severe Alzheimer’s disease in adult patients. GNH USA supplies Memantina Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Memantine Hydrochloride used for?

Memantina Aurovitas is an NMDA receptor antagonist used in the management of Alzheimer’s disease and related cognitive decline. - Alzheimer’s disease (moderate to severe): helps maintain cognition and daily functioning in affected patients. - Behavioral symptoms of Alzheimer’s disease: may reduce agitation and aggression associated with the condition. - Functional decline in Alzheimer’s disease: supports activities of daily living and slows functional deterioration.

What are the side effects of Memantine Hydrochloride?

Common Side Effects: - Dizziness: mild to moderate sensation of light‑headedness. - Headache: transient pain often reported during initiation. - Constipation: reduced bowel movements, manageable with diet. - Fatigue: feeling of tiredness or reduced energy. - Hypertension: occasional increase in blood pressure. - Confusion: temporary disorientation, especially in early treatment.

Serious or Rare Side Effects: - Seizures: rare occurrence requiring immediate medical attention. - Stevens‑Johnson syndrome: severe skin reaction, discontinue use. - Hepatic dysfunction: elevated liver enzymes, monitor liver function. - Cardiac arrhythmia: irregular heart rhythm, especially in patients with pre‑existing conditions. - Suicidal thoughts: emergent mood changes, seek psychiatric evaluation. - Severe hypotension: marked drop in blood pressure, may cause fainting.

What precautions apply to Memantine Hydrochloride?

Memantina Aurovitas should be used with caution in specific clinical situations. - Renal impairment: dose adjustment may be required based on kidney function. - History of seizures: monitor closely for increased seizure activity. - Cardiovascular disease: observe blood pressure and heart rate regularly. - Concurrent NMDA antagonists: avoid co‑administration to reduce additive neurotoxicity. - Pregnancy and lactation: safety unknown; avoid unless benefits outweigh risks. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

What does Memantine Hydrochloride interact with?

Memantina Aurovitas may interact with several medicines; careful review is advised. Major Interactions (Avoid): - Amantadine: additive NMDA antagonism may increase neurotoxicity. - Ketamine: combined NMDA blockade can cause severe central nervous system effects. - Other NMDA antagonists (e.g., dextromethorphan): risk of additive toxicity. Moderate Interactions (Monitor Closely): - Antihypertensives: may enhance hypotensive effect, monitor blood pressure. - Diuretics: increased risk of dehydration and dizziness. - CNS depressants (e.g., benzodiazepines): may increase sedation and impair coordination.

Frequently asked questions

What is Memantina Aurovitas used for?+
Memantina Aurovitas contains memantine hydrochloride and is prescribed for the symptomatic treatment of moderate to severe Alzheimer’s disease. It helps improve cognition, memory, and daily functioning in patients with this form of dementia.
How does memantine work in the brain?+
Memantine acts as a non‑competitive antagonist at NMDA receptors, reducing excessive calcium influx that leads to neuronal excitotoxicity. By moderating this pathway, it helps protect neurons and supports synaptic activity, which can slow cognitive decline in Alzheimer’s disease.
What is the usual dose of Memantina Aurovitas?+
The specific dose and titration schedule for Memantina Aurovitas are determined by the prescribing clinician based on the patient’s condition, renal function, and tolerability. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Memantina Aurovitas safe during pregnancy or breastfeeding?+
Safety data for memantine in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and under close medical supervision.
How do I order Memantina Aurovitas from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.
How does Memantina Aurovitas compare with other Alzheimer’s drugs?+
Memantine belongs to the NMDA receptor antagonist class, differing from cholinesterase inhibitors such as donepezil. While cholinesterase inhibitors increase acetylcholine levels, memantine reduces excitotoxicity. Both classes may be used together for additive benefits, but the choice depends on disease stage and individual patient response.
What are the storage and handling requirements for Memantina Aurovitas?+
Memantina Aurovitas should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiration date printed on the label.
How is Memantina Aurovitas administered?+
The medication is taken orally, usually once daily, with or without food as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.
What are the most serious risks associated with Memantina Aurovitas?+
Serious adverse events, though rare, include seizures, severe skin reactions such as Stevens‑Johnson syndrome, hepatic dysfunction, cardiac arrhythmias, and emergent suicidal thoughts. Patients should seek immediate medical attention if any of these symptoms occur.
Who should not use Memantina Aurovitas?+
Memantina Aurovitas is contraindicated in patients with known hypersensitivity to memantine or any excipients in the formulation. Caution is advised for individuals with severe renal impairment, uncontrolled seizures, or those taking other NMDA antagonists, unless a prescriber determines the benefits outweigh the risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Memantine Hydrochloride
Route
Oral Use
Manufacturer
Generis Farmacêutica, S.A.
Origin
EU

Related products