Meloxicam Aurobindo

Meloxicam, the active ingredient in Meloxicam Aurobindo, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It is indicated for the management of osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis and acute pain in adult patients.

GNH USA supplies Meloxicam Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved products to a global network of healthcare providers, including public and private sector institutions.

Meloxicam is an NSAID that reduces inflammation and pain by targeting the cyclooxygenase pathway.

- Osteoarthritis: reduces joint pain and improves mobility. - Rheumatoid arthritis: decreases synovial inflammation and slows disease progression. - Juvenile rheumatoid arthritis: alleviates pain and swelling in pediatric patients. - Ankylosing spondylitis: mitigates spinal stiffness and discomfort. - Acute pain: provides rapid relief of moderate to severe pain episodes.

Common Side Effects: - Dyspepsia: stomach discomfort or indigestion. - Nausea: feeling of sickness or urge to vomit. - Headache: mild to moderate head pain. - Dizziness: sensation of light‑headedness or unsteadiness. - Peripheral edema: mild swelling of the lower limbs. - Elevated blood pressure: modest increase in systolic or diastolic values.

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding: potentially life‑threatening hemorrhage. - Cardiovascular events: increased risk of heart attack or stroke. - Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatic injury: elevated liver enzymes or hepatitis. - Renal impairment: acute kidney injury or worsening of chronic kidney disease.

Before initiating therapy, consider the following precautions: - Assess renal function: monitor serum creatinine and eGFR. - Evaluate hepatic status: check liver enzymes in patients with liver disease. - Monitor blood pressure: watch for hypertension, especially in cardiovascular risk groups. - Review concomitant NSAID or anticoagulant use: avoid additive bleeding risk. - Use lowest effective dose: limit duration to the shortest period needed for symptom control. - Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture and direct sunlight.

Meloxicam may interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Lithium: meloxicam can raise lithium serum concentrations. - Methotrexate: heightened methotrexate toxicity. - SSRIs or SNRIs: additive bleeding risk.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in renal function. - Diuretics: may diminish antihypertensive effect. - Cyclosporine: increased nephrotoxicity risk.