Europe — EMA
Melatonina Perrigo
GNH USA supplies Melatonina Perrigo (Melatonin), a hormone supplement for sleep‑wake rhythm disorders such as jet lag and shift work.
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What is Melatonin?
Melatonin, the active ingredient in Melatonina Perrigo, is a hormone supplement presented as an oral tablet for oral use. It helps regulate the circadian rhythm and may be used to support sleep timing in adults.
GNH USA supplies Melatonina Perrigo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Melatonin used for?
Melatonin is used to address disorders of the sleep‑wake cycle and related circadian rhythm disturbances.
- Jet lag: helps realign the internal clock after rapid time‑zone travel. - Shift work disorder: supports sleep onset for workers on rotating or night shifts. - Delayed sleep phase disorder: advances bedtime in individuals with late‑night sleep patterns.
What are the side effects of Melatonin?
Melatonin is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Drowsiness: feeling unusually sleepy during the day. - Headache: mild to moderate head pain. - Dizziness: sensation of light‑headedness. - Nausea: mild stomach upset.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Mood changes: depression or increased anxiety. - Severe abdominal pain: persistent or worsening stomach discomfort.
What precautions apply to Melatonin?
When considering melatonin therapy, several safety points should be reviewed.
- Pregnancy: consult a healthcare professional before use. - Breastfeeding: discuss potential exposure with a physician. - Concomitant CNS depressants: monitor for additive sedation. - Autoimmune disorders: use with caution as melatonin may modulate immune activity. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.
What does Melatonin interact with?
Melatonin may interact with other medicines; the significance varies.
Major Interactions (Avoid): - Anticoagulants: melatonin may increase bleeding risk. - Immunosuppressants: potential reduction in therapeutic effect.
Moderate Interactions (Monitor Closely): - Caffeine: may diminish melatonin's sleep‑promoting action. - Alcohol: can enhance sedative effects. - Sedative antihistamines: may increase daytime drowsiness.
