Melatonin Al

Melatonin, the active ingredient in Melatonin Al, is a melatonin receptor agonist presented as a unknown/unknown for oral use. It treats insomnia, jet lag and sleep‑wake rhythm disorders in adults. GNH USA supplies Melatonin Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Melatonin Al belongs to the melatonin receptor agonist class and is used to manage sleep‑related disorders. - Insomnia: helps initiate and maintain sleep, improving sleep quality in individuals with difficulty falling asleep. - Jet lag: assists the body’s circadian adjustment after rapid time‑zone travel, reducing sleep disruption. - Sleep‑wake rhythm disorders: stabilises abnormal sleep patterns, supporting a regular sleep‑wake cycle.

Melatonin is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Drowsiness or daytime sleepiness - Headache - Dizziness - Nausea or mild gastrointestinal discomfort - Vivid dreams or altered dream patterns - Mild abdominal cramps

Serious or Rare Side Effects: - Allergic reactions such as rash, itching or swelling - Severe dizziness or vertigo - Mood changes including depression or anxiety - Hallucinations or vivid nightmares - Respiratory depression (rare) - Severe abdominal pain or vomiting

Melatonin should be used with consideration of individual health status and concomitant therapies. - Assess medical history: evaluate existing sleep disorders and comorbid conditions before use. - Review concomitant medications: check for potential additive CNS depressant effects. - Avoid use in children unless specifically prescribed: safety data in pediatric populations are limited. - Use caution in hepatic impairment: metabolism may be altered, requiring monitoring. - Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Melatonin may interact with other agents that affect the central nervous system or metabolic pathways.

Major Interactions (Avoid): - Benzodiazepines or other sedatives: risk of excessive sedation. - Anticoagulants (e.g., warfarin): possible increase in bleeding risk. - Immunosuppressants (e.g., cyclosporine): may alter drug levels.

Moderate Interactions (Monitor Closely): - Alcohol: can enhance drowsiness. - Antihistamines: may increase sedation. - Oral contraceptives: melatonin may affect hormone metabolism.