Melatonin Ab

Melatonin, the active ingredient in Melatonin Ab, is a melatonin receptor agonist presented as an oral dosage form for oral use. It helps regulate circadian rhythm and promotes sleep onset, addressing insomnia and related sleep‑wake rhythm disorders, including jet lag, in adult patients.

GNH USA supplies Melatonin Ab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and adherence to European Union manufacturing standards. Our distribution network provides reliable access across multiple regions.

Melatonin is used to address sleep‑related conditions by acting on the melatonin receptor pathway.

- Insomnia: Improves sleep onset and reduces nighttime awakenings. - Sleep‑wake rhythm disorders: Helps synchronize disrupted circadian rhythms. - Jet lag: Facilitates adjustment to new time zones and reduces fatigue after long‑distance travel.

Melatonin is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Drowsiness - Headache - Dizziness - Nausea - Mild vivid dreams

Serious or Rare Side Effects: - Allergic reaction (rash, itching, swelling) - Severe skin eruption - Mood changes or depression - Marked daytime sleepiness affecting activities - Rare cases of hypotension

When using Melatonin Ab, consider the following precautions.

- Assess renal function: adjust use in severe impairment. - Avoid operating machinery if drowsy. - Consult physician if taking anticoagulants or other CNS depressants. - Use with caution in elderly patients due to increased sensitivity. - Pregnancy and lactation: safety not established; discuss with healthcare provider. - Store at ambient temperature: keep in original container, protect from moisture and light.

Melatonin may interact with other medicines; monitor accordingly.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): may increase bleeding risk. - Immunosuppressants (e.g., cyclosporine): may alter melatonin metabolism.

Moderate Interactions (Monitor Closely): - CNS depressants (e.g., benzodiazepines): additive sedation. - Antidepressants (e.g., SSRIs): may affect sleep architecture. - Oral contraceptives: may increase melatonin plasma levels.