Melatonin-Valerosolv Teva Gyógyszergyár Zrt

Melatonin, the active ingredient in Melatonin-Valerosolv Teva Gyógyszergyár Zrt, is a melatonin receptor agonist presented as an oral tablet for oral use. It is used to treat insomnia and sleep‑wake rhythm disorders in adults. GNH USA supplies Melatonin-Valerosolv Teva Gyógyszergyár Zrt as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Melatonin is a melatonin receptor agonist used to address disorders of the sleep‑wake cycle. Insomnia: helps initiate and maintain sleep in individuals with difficulty falling asleep. Sleep‑wake rhythm disorders: assists in normalising disrupted circadian rhythms. Delayed sleep phase syndrome: advances sleep onset to align with desired bedtime.

Melatonin is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Headache: mild to moderate pain often resolving without intervention. - Dizziness: transient sensation of light‑headedness. - Daytime sleepiness: residual drowsiness after nighttime dosing. - Nausea: occasional gastrointestinal discomfort. - Mild gastrointestinal upset: includes abdominal cramps or loose stools.

Serious or Rare Side Effects: - Allergic reactions: rash, itching, or swelling of the face, lips, or tongue. - Severe rash: including Stevens‑Johnson syndrome. - Mood changes: depression or agitation in susceptible individuals. - Hallucinations: visual or auditory disturbances. - Severe hypotension: marked drop in blood pressure leading to faintness.

Melatonin should be used with consideration of individual health status and potential interactions. - Assess renal function: adjust use in patients with severe renal impairment. - Avoid concurrent CNS depressants: increased risk of excessive sedation. - Caution in shift‑work or jet‑lag situations: timing of administration is critical. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Store at ambient temperature: keep in the original container, protect from moisture and light.

Melatonin may interact with other medications, requiring monitoring.

Major Interactions (Avoid): - CNS depressants (e.g., benzodiazepines, alcohol): additive sedative effect. - Anticoagulants (e.g., warfarin): potential increase in bleeding risk.

Moderate Interactions (Monitor Closely): - Antidepressants (e.g., fluoxetine): may alter melatonin metabolism. - Caffeine: can diminish melatonin’s sleep‑promoting effect. - Beta‑blockers: may reduce endogenous melatonin levels. - Antihistamines: may increase drowsiness when combined.