Mefenamic Acid

Mefenamic Acid, the active ingredient in Mefenamic Acid, is a NSAID presented as an oral tablet for oral use. It provides relief of mild to moderate pain, menstrual cramps, and inflammatory conditions in adult patients.

GNH USA supplies Mefenamic Acid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and offers reliable global distribution. We support regulatory compliance and provide technical documentation as required.

Mefenamic Acid is indicated for conditions involving pain and inflammation, acting through inhibition of prostaglandin synthesis.

- Mild to moderate pain: provides analgesic relief for everyday aches. - Menstrual pain (dysmenorrhea): reduces uterine cramping and discomfort. - Inflammatory conditions (e.g., arthritis): decreases inflammation and associated pain.

Mefenamic Acid may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea: occasional upset stomach. - Abdominal pain: discomfort in the stomach area. - Headache: mild to moderate head pain. - Dizziness: feeling light‑headed or unsteady.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding: severe stomach or intestinal lesions. - Renal impairment: reduced kidney function. - Severe skin reactions (e.g., Stevens‑Johnson syndrome): extensive rash or blistering. - Hepatic dysfunction: abnormal liver enzyme elevations. - Anaphylaxis: life‑threatening allergic reaction. - Blood dyscrasias: abnormal blood cell counts.

When prescribing Mefenamic Acid, clinicians should consider several precautionary measures to minimize risk.

- Renal function: monitor in patients with existing kidney disease. - Gastrointestinal risk: avoid in individuals with a history of ulcer or bleeding. - Cardiovascular health: use cautiously in patients with heart disease. - Pregnancy and lactation: safety not established; avoid unless clearly needed. - Drug interactions: review concomitant NSAIDs, anticoagulants, and SSRIs. - Store at ambient temperature: keep in the original pack, protect from moisture.

Mefenamic Acid can interact with other medicines, requiring attention to avoid harmful effects.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely): - ACE inhibitors: possible reduction in renal function. - Diuretics: increased risk of renal impairment. - Lithium: potential elevation of serum lithium levels.