Medovir

Aciclovir, the active ingredient in Medovir, is an antiviral presented as a topical formulation for cutaneous use. It treats herpes virus infections of the skin and mucous membranes in adults and children.

GNH USA supplies Medovir as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Aciclovir topical therapy is used to manage infections caused by herpes viruses affecting the skin and mucous membranes.

- Herpes labialis: reduces lesion duration and pain when applied at the first sign of an outbreak. - Genital herpes: alleviates symptoms and promotes faster healing of genital lesions. - Herpes zoster (topical treatment): provides local antiviral activity to lessen skin lesions and discomfort.

Topical aciclovir may cause local skin reactions, ranging from mild irritation to rare severe hypersensitivity.

Common Side Effects: - Burning sensation at the application site. - Stinging or itching. - Redness or erythema. - Dryness or peeling of the skin. - Mild rash. - Local tenderness.

Serious or Rare Side Effects: - Allergic contact dermatitis. - Severe skin reactions such as Stevens‑Johnson syndrome. - Ocular irritation if applied near the eye. - Systemic absorption leading to renal toxicity (rare). - Anaphylactic reaction. - Unexplained fever with rash.

Before using Medovir, consider the following precautions to ensure safe and effective treatment.

- Assess renal function: adjust use if significant renal impairment is present. - Avoid extensive damaged skin: limit application to small, intact lesions. - Do not apply near eyes or mucous membranes: risk of irritation. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Store at room temperature: keep in the original container, protect from moisture and light.

Aciclovir can interact with other medicines, affecting its concentration or the safety of co‑administered drugs.

Major Interactions (Avoid): - Probenecid: reduces renal clearance, increasing aciclovir plasma levels. - Didanosine: may enhance didanosine toxicity. - Nephrotoxic agents (e.g., aminoglycosides): combined use can worsen renal function.

Moderate Interactions (Monitor Closely): - Cimetidine: may increase aciclovir levels modestly. - NSAIDs: monitor renal function when used together. - Other antivirals (e.g., valacyclovir): assess cumulative antiviral effect. - Immunosuppressants: watch for altered infection risk.