GNH USA

Europe — EMA

Medovert

GNH USA supplies Medovert (Cinnarizine/Dimenhydrinate), a antihistamine for motion sickness, vertigo and nausea. Request a quote for global supply today.

Cinnarizine, Dimenhydrinate

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What is Cinnarizine, Dimenhydrinate?

Cinnarizine and Dimenhydrinate, the active ingredients in Medovert, are antihistamines presented as an oral tablet for oral use. They help reduce vestibular stimulation and prevent nausea and vomiting associated with motion sickness, vertigo, and other causes in adults and adolescents over 12 years of age.

GNH USA supplies Medovert as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers, ensuring consistent product availability.

What is Cinnarizine, Dimenhydrinate used for?

Medovert, a combination antihistamine, is used to manage conditions that involve vestibular disturbance and nausea.

- Motion sickness: reduces the sensation of nausea and vomiting during travel by stabilizing the inner ear signals. - Vertigo: alleviates dizziness and spinning sensations associated with vestibular disorders. - Nausea: provides relief from nausea caused by various triggers, including medication side effects.

What are the side effects of Cinnarizine, Dimenhydrinate?

Like many antihistamines, Medovert may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Drowsiness: feeling of sleepiness or reduced alertness. - Dry mouth: decreased salivation leading to a dry oral cavity. - Gastrointestinal discomfort: mild nausea, abdominal cramps or dyspepsia. - Headache: mild to moderate head pain.

Serious or Rare Side Effects: - Extrapyramidal symptoms: involuntary muscle movements or tremor, especially with prolonged use. - Allergic reactions: rash, itching, swelling, or anaphylaxis in rare cases. - Cardiac arrhythmia: irregular heart rhythm reported rarely, requiring medical attention.

What precautions apply to Cinnarizine, Dimenhydrinate?

Before using Medovert, consider the following safety measures and warnings. - Contraindication: avoid use in individuals with known hypersensitivity to cinnarizine, dimenhydrinate or other antihistamines. - Sedation risk: do not operate machinery or drive until you know how the medication affects you. - Age limitation: use with caution in children under 12 years; safety not established. - Drug interactions: consult a healthcare professional before combining with other central nervous system depressants or anticholinergic drugs. - Pregnancy and lactation: discuss potential risks with a physician; data are limited. - Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and light.

What does Cinnarizine, Dimenhydrinate interact with?

Medovert can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - CNS depressants: concurrent use with alcohol, benzodiazepines or opioids may enhance sedation and respiratory depression. - Anticholinergic agents: combined use can increase risk of dry mouth, urinary retention and blurred vision.

Moderate Interactions (Monitor Closely): - MAO inhibitors: may potentiate antihistaminic effects, requiring dose adjustment. - Antidepressants (SSRIs, TCAs): may increase risk of serotonin syndrome or enhanced side effects. - Antihypertensive drugs: cinnarizine may have mild blood‑pressure‑lowering effects, potentially augmenting antihypertensive therapy.

Frequently asked questions

What is Medovert used for?+
Medovert is an over‑the‑counter combination antihistamine indicated for the relief of motion sickness, vertigo‑related dizziness, and nausea caused by various triggers. It is commonly used by travelers, patients with vestibular disorders, and individuals experiencing nausea from medication side effects.
How does cinnarizine/dimenhydrinate work?+
Cinnarizine blocks calcium channels and antagonizes H1‑histamine receptors, reducing vestibular hair‑cell excitability. Dimenhydrinate acts as an H1‑receptor antagonist and anticholinergic. Together they dampen vestibular stimulation and suppress the central vomiting centre, helping to prevent nausea and vomiting.
What is the usual dose of Medovert?+
The appropriate dose of Medovert is determined by a qualified prescriber based on the patient’s age, condition, and response to therapy. Healthcare professionals follow local labeling and clinical guidelines to select the correct regimen for each individual.
Is Medovert safe during pregnancy or breastfeeding?+
Safety data for cinnarizine and dimenhydrinate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Medovert.
How do I order Medovert from GNH USA?+
To place an order, submit an enquiry on the Medovert product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Medovert compare with the main alternative drug or class?+
Medovert combines cinnarizine and dimenhydrinate, offering both calcium‑channel blockade and antihistamine effects. Compared with single‑agent antihistamines such as meclizine, the combination may provide broader vestibular stabilization, but individual response varies. Clinicians choose based on efficacy, tolerability, and patient‑specific factors.
How should Medovert be stored and handled?+
Medovert tablets should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture and direct light, and keep it out of reach of children.
How is Medovert administered?+
Medovert is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the prescriber’s instructions regarding timing relative to meals or travel.
What are the most serious risks to watch for while taking Medovert?+
Serious adverse reactions, although rare, include extrapyramidal symptoms such as involuntary muscle movements, severe allergic responses like anaphylaxis, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience unusual muscle twitching, rash, swelling, difficulty breathing, or irregular heartbeats.
Who should not use Medovert?+
Medovert should be avoided by individuals with known hypersensitivity to cinnarizine, dimenhydrinate, or any component of the formulation. It is also contraindicated in patients taking certain strong CNS depressants or anticholinergic drugs without medical supervision, and caution is advised for children under 12 years of age.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Cinnarizine, Dimenhydrinate
Route
Oral Use
Manufacturer
Medochemie Ltd.
Origin
EU

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