Medorphan

Dextromethorphan Hydrobromide, the active ingredient in Medorphan, is an antitussive (NMDA receptor antagonist) presented as an oral dosage form for oral use. It provides temporary relief of cough caused by minor throat and bronchial irritation in adults and children over two years of age. It is commonly used for cough associated with the common cold.

GNH USA supplies Medorphan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution.

Dextromethorphan Hydrobromide acts on the central cough reflex pathway to suppress coughing. - Cough due to minor throat irritation: provides temporary relief of the cough reflex. - Cough associated with common cold: reduces the frequency of coughing episodes. - Bronchial irritation cough: helps alleviate cough caused by mild bronchial irritation.

Common Side Effects: - Nausea - Dizziness - Dry mouth - Drowsiness

Serious or Rare Side Effects: - Allergic reactions such as rash, swelling, or anaphylaxis - Serotonin syndrome when combined with serotonergic agents - Hallucinations or other psychotic symptoms

Before using Medorphan, consider the following precautions: - Dosage adjustment in hepatic impairment: reduce dose as advised by the prescriber. - Avoid use in children under two years: not recommended for this age group. - Do not operate machinery or drive: may cause drowsiness or impaired coordination. - Avoid concurrent use with MAO inhibitors: risk of severe serotonin syndrome. - Store at room temperature below 25°C: keep in the original pack, protect from moisture.

Dextromethorphan may interact with several medicines. Monitor the following: Major Interactions (Avoid): - MAO inhibitors: risk of severe serotonin syndrome. - Selective serotonin reuptake inhibitors (SSRIs): increased risk of serotonin syndrome. - Other NMDA antagonists: additive central nervous system effects. Moderate Interactions (Monitor Closely): - Alcohol: may enhance drowsiness. - Antihistamines: may increase sedation. - CYP2D6 inhibitors (e.g., fluoxetine): may raise dextromethorphan plasma levels.