Meclodin

Clotrimazole and Metronidazole, the active ingredients in Meclodin, are an antifungal and an antiprotozoal presented as a vaginal formulation for intravaginal use. The combination treats common vaginal infections caused by fungi, anaerobic bacteria, or protozoa in adult women.

GNH USA supplies Meclodin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality manufacturing and regulatory compliance for export to global markets.

Meclodin combines clotrimazole and metronidazole to treat common vaginal infections caused by fungi, bacteria, or protozoa.

- Vaginal candidiasis: eradicates Candida species and relieves itching, discharge and irritation. - Bacterial vaginosis: reduces anaerobic bacterial overgrowth and helps restore normal vaginal flora. - Trichomoniasis: eliminates Trichomonas vaginalis infection and improves abnormal discharge.

Meclodin may cause local and systemic adverse reactions.

Common Side Effects: - Vaginal irritation or burning - Itching or mild pruritus - Increased vaginal discharge - Unpleasant odor from the product - Mild lower‑abdominal cramps - Headache

Serious or Rare Side Effects: - Allergic reaction (rash, swelling, hives) - Severe vaginal ulceration or necrosis - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Hepatic dysfunction or jaundice - Anaphylaxis - Severe headache or neurological symptoms

Before using Meclodin, consider the following precautions.

- Pregnancy: consult a healthcare professional before use. - Breastfeeding: use with caution; metronidazole may be excreted in breast milk. - Allergies: avoid if known hypersensitivity to clotrimazole, metronidazole, or excipients. - Alcohol consumption: metronidazole can cause a disulfiram‑like reaction; avoid alcohol. - Severe liver disease: use only under medical supervision. - Store at room temperature: keep in the original packaging, protect from moisture and direct heat.

Meclodin can interact with other medicines; monitor as indicated.

Major Interactions (Avoid): - Alcohol: may trigger severe disulfiram‑like reaction with metronidazole. - Live vaginal probiotic products: may reduce therapeutic efficacy. - Warfarin: metronidazole can potentiate anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely): - Oral contraceptives: metronidazole may increase plasma hormone levels. - Other azole antifungals: potential additive toxicity. - Lithium: metronidazole may raise lithium concentrations, requiring serum level monitoring.