GNH USA

Europe — EMA

Mayra (Dienogest, Ethinylestradiol)

GNH USA supplies Mayra (Dienogest/Ethinylestradiol), a combined oral contraceptive for prevention of pregnancy and treatment of menstrual disorders.

Dienogest, Ethinylestradiol

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What is Dienogest, Ethinylestradiol?

Dienogest/Ethinylestradiol, the active ingredient in Mayra, is a combined oral contraceptive presented as an oral tablet for oral use. It is indicated for prevention of pregnancy and treatment of menstrual disorders in women of reproductive age.

GNH USA supplies Mayra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Dienogest, Ethinylestradiol used for?

Mayra, a combined oral contraceptive, acts on the hormonal regulation of the menstrual cycle.

- Prevention of pregnancy: provides reliable contraceptive protection when taken as prescribed. - Treatment of menstrual disorders: helps regulate cycle length and reduce abnormal uterine bleeding. - Management of dysmenorrhea: alleviates painful menstrual cramps through hormonal stabilization. - Regulation of irregular cycles: promotes predictable bleeding patterns.

What are the side effects of Dienogest, Ethinylestradiol?

Mayra may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Nausea - Headache - Breast tenderness - Spotting or irregular bleeding - Weight gain - Mood changes

Serious or Rare Side Effects: - Deep vein thrombosis - Pulmonary embolism - Stroke - Myocardial infarction - Severe allergic reaction (anaphylaxis) - Hepatic tumor (rare)

What precautions apply to Dienogest, Ethinylestradiol?

Before prescribing Mayra, clinicians should consider several safety precautions.

- Pregnancy: contraindicated; avoid use during pregnancy. - Smoking: women over 35 who smoke should not use this product. - Thromboembolic history: avoid in patients with past clotting disorders. - Hypertension: not recommended for uncontrolled high blood pressure. - Liver disease: use with caution in hepatic impairment. - Store at room temperature: keep in original packaging, protect from moisture and light.

What does Dienogest, Ethinylestradiol interact with?

Mayra can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid): - Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may reduce contraceptive efficacy. - Rifampicin and other strong inducers: may lower hormone levels, increasing risk of pregnancy. - St. John’s wort: may decrease effectiveness of hormonal contraception.

Moderate Interactions (Monitor Closely): - Tetracycline antibiotics: may slightly reduce contraceptive effectiveness. - Antifungal ketoconazole: may increase hormone concentrations, raising side‑effect risk. - SSRIs (e.g., fluoxetine): may increase incidence of mood‑related side effects.

Frequently asked questions

What is Mayra used for?+
Mayra is a combined oral contraceptive that is prescribed to prevent pregnancy and to treat menstrual disorders such as irregular bleeding and painful periods. It provides hormonal regulation that helps achieve reliable contraception while improving cycle regularity.
How does Dienogest/Ethinylestradiol work in Mayra?+
The formulation contains dienogest, a progestogen, and ethinylestradiol, an estrogen. Together they suppress the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), preventing ovulation. They also thicken cervical mucus and alter the endometrial lining, reducing the chance of sperm entry and implantation.
What is the usual dose of Mayra?+
The dosing regimen for Mayra is determined by the prescribing healthcare professional. Typically, combined oral contraceptives are taken once daily at the same time, but the exact schedule and any missed‑dose instructions should be provided by the prescriber.
Is Mayra safe to use during pregnancy or breastfeeding?+
Mayra is contraindicated during pregnancy and should not be started in women who are already pregnant. Limited data are available for breastfeeding; therefore, the benefit‑risk balance must be evaluated by a clinician before use in lactating women.
How do I order Mayra from GNH USA?+
To request Mayra, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Mayra compare with other combined oral contraceptives?+
Mayra contains dienogest, which has a higher anti‑androgenic activity than some older progestins such as levonorgestrel. This can result in a different side‑effect profile, particularly regarding acne and weight changes, while offering comparable contraceptive efficacy.
What are the storage and handling requirements for Mayra?+
Mayra tablets should be stored at room temperature, below 25 °C, in the original blister pack. Protect them from excess moisture and direct sunlight to maintain product stability throughout the shelf life.
How is Mayra administered?+
Mayra is taken orally, usually as a single tablet each day. It should be taken at the same time each day to maintain consistent hormone levels and maximize contraceptive effectiveness.
What are the most serious risks associated with Mayra?+
The most serious adverse events include thromboembolic disorders such as deep‑vein thrombosis, pulmonary embolism, stroke, and myocardial infarction. These risks are higher in smokers over 35, women with a history of clotting disorders, or those with uncontrolled hypertension.
Who should not use Mayra?+
Mayra should not be used by women who are pregnant, have a history of thromboembolic disease, uncontrolled hypertension, severe liver disease, known or suspected breast cancer, or who are smokers aged 35 years or older. Contraindications must be confirmed by a qualified healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Dienogest, Ethinylestradiol
Route
Oral Use
Manufacturer
Exeltis Germany Gmbh
Origin
EU

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