GNH USA

Europe — EMA

Mayra

GNH USA supplies Mayra (Dienogest/Ethinylestradiol), a combined oral contraceptive for contraception and menstrual cycle regulation.

Dienogest, Ethinylestradiol

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What is Dienogest, Ethinylestradiol?

Dienogest/Ethinylestradiol, the active ingredient in Mayra, is a combined oral contraceptive presented as an oral tablet for oral use. It provides hormonal contraception and helps regulate menstrual cycles in women of reproductive age.

GNH USA supplies Mayra as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Dienogest, Ethinylestradiol used for?

Mayra is a combined hormonal contraceptive that acts on the reproductive hormone pathway to prevent pregnancy and manage menstrual disorders. - Contraception: prevents pregnancy by inhibiting ovulation and altering cervical mucus. - Regulation of menstrual cycles: reduces irregular bleeding and provides predictable cycle control. - Management of dysmenorrhea: alleviates painful menstrual cramps through hormonal stabilization.

What are the side effects of Dienogest, Ethinylestradiol?

Mayra may cause a range of adverse reactions. Most are mild and transient, but rare serious events can occur.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Headache: tension‑type or migraine‑like. - Breast tenderness: swelling or discomfort. - Weight gain: modest increase in body weight. - Mood changes: irritability or mood swings. - Spotting: irregular light bleeding.

Serious or Rare Side Effects: - Venous thromboembolism: blood clots in deep veins. - Arterial thrombosis: clot formation in arteries. - Hypertension: elevated blood pressure. - Liver disorders: jaundice or hepatic dysfunction. - Severe allergic reactions: rash, swelling, anaphylaxis. - Gallbladder disease: inflammation or stones.

What precautions apply to Dienogest, Ethinylestradiol?

Before prescribing Mayra, clinicians should evaluate patient history and risk factors. - Assess medical history: identify thrombosis, cardiovascular, or liver disease. - Avoid smoking: especially in women over 35 years of age. - Monitor blood pressure: hypertension may develop during therapy. - Review medication list: potential interactions can affect efficacy. - Consider liver function: contraindicated in severe hepatic impairment. - Store at ambient temperature: keep below 25°C, protect from moisture.

What does Dienogest, Ethinylestradiol interact with?

Mayra can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid): - Anticoagulants (warfarin): may reduce anticoagulant effect. - Antiepileptics (carbamazepine, phenytoin): increase hormone metabolism, lowering contraceptive efficacy. - Rifampicin and other strong enzyme inducers: may cause contraceptive failure.

Moderate Interactions (Monitor Closely): - Antibiotics (tetracycline, penicillins): may slightly reduce hormonal effect. - SSRIs (fluoxetine, sertraline): can increase hormone levels. - Herbal supplements (St. John's wort, ginseng): possible enzyme induction affecting efficacy.

Frequently asked questions

What is Mayra used for?+
Mayra is prescribed as a combined hormonal contraceptive to prevent pregnancy and to help regulate menstrual cycles. It is indicated for women of reproductive age who require reliable birth control and for those seeking cycle control or relief from menstrual irregularities.
How does Dienogest/Ethinylestradiol work?+
The ethinylestradiol component suppresses follicle‑stimulating hormone, while dienogest blocks the luteinizing hormone surge, together preventing ovulation. The formulation also thickens cervical mucus and alters the endometrial lining, creating conditions that are unfavorable for fertilisation and implantation.
What is the usual dose of Mayra?+
The dosing regimen for Mayra is determined by the prescribing clinician based on individual health status and treatment goals. Typically, a standard combined oral contraceptive schedule is followed, but the exact number of tablets per cycle and any placebo days are set by the prescriber.
Is Mayra safe to use during pregnancy or while breastfeeding?+
Mayra is contraindicated during pregnancy because it is intended to prevent conception. If pregnancy occurs, the product should be discontinued. While limited data exist for breastfeeding, combined oral contraceptives are generally used with caution; a healthcare professional should assess the risk‑benefit ratio for nursing mothers.
How do I order Mayra from GNH USA?+
To request Mayra, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any special handling), and necessary import documentation.
How does Mayra compare with other combined oral contraceptives?+
Mayra contains the progestogen dienogest, which offers a slightly lower androgenic profile compared with some older progestins, potentially resulting in fewer acne‑related side effects. Its estrogen component, ethinylestradiol, is standard for combined pills, providing comparable contraceptive efficacy and cycle control to other products in the same class.
How should Mayra be stored and handled?+
Mayra tablets should be stored at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.
How is Mayra administered?+
Mayra is taken orally, usually once daily at the same time each day. The tablets are swallowed with water and should be taken with or without food as directed by the prescriber. Consistent daily intake maximises contraceptive effectiveness.
What are the most serious risks associated with Mayra?+
The most serious risks include venous or arterial thromboembolism, hypertension, severe liver disease, and rare allergic reactions such as anaphylaxis. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should be closely monitored or may need alternative contraception.
Who should not use Mayra?+
Mayra is contraindicated in women with known or suspected pregnancy, active thromboembolic disease, uncontrolled hypertension, severe liver disease, or a history of estrogen‑dependent tumors. It should also be avoided by smokers over 35 years of age and by individuals with known hypersensitivity to any component of the tablet.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dienogest, Ethinylestradiol
Route
Oral Use
Manufacturer
Exeltis Germany Gmbh
Origin
EU

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