Maxipirin

Acetylsalicylic Acid, the active ingredient in Maxipirin, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It provides analgesic, antipyretic, anti‑inflammatory and antiplatelet effects and is used in adults for pain, fever, inflammation and cardiovascular event prevention.

GNH USA supplies Maxipirin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

Maxipirin (acetylsalicylic acid) is used in several therapeutic areas that involve prostaglandin‑mediated processes.

- Pain relief: reduces mild to moderate pain such as headache, musculoskeletal aches, and dental pain. - Fever reduction: lowers elevated body temperature associated with infectious or inflammatory conditions. - Inflammation reduction: alleviates inflammatory swelling in conditions like arthritis. - Prevention of thrombotic cardiovascular events: inhibits platelet aggregation to lower risk of heart attack and stroke in at‑risk patients.

Acetylsalicylic acid may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Gastric irritation: heartburn or gastritis. - Minor bleeding: easy bruising or nosebleeds. - Headache: transient headache episodes.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding: severe stomach or intestinal bleeding. - Allergic reactions: rash, itching, or anaphylaxis. - Hepatic or renal impairment: signs of liver or kidney dysfunction. - Reye’s syndrome: rare but serious condition in children with viral illness.

When prescribing or dispensing Maxipirin, several precautions should be observed to minimize risk. - Assess gastrointestinal risk: evaluate history of ulcers, bleeding or NSAID use. - Evaluate bleeding risk: consider concurrent anticoagulants or clotting disorders. - Monitor renal function: avoid in patients with severe kidney impairment. - Pregnancy consideration: avoid use in the third trimester due to fetal risks. - Contraindications: do not use in individuals with known hypersensitivity to aspirin or other NSAIDs. - Store at ambient temperature: keep below 25 °C in the original container, protected from moisture and direct sunlight.

Acetylsalicylic acid can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Selective COX‑2 inhibitors (e.g., celecoxib): heightened gastrointestinal toxicity. - SSRIs or SNRIs: elevated bleeding tendency.

Moderate Interactions (Monitor Closely): - Corticosteroids: may exacerbate gastric ulcer risk. - Diuretics (e.g., thiazides): may reduce renal clearance of aspirin. - Methotrexate: aspirin can increase methotrexate toxicity.