Maxipirin

Acetylsalicylic Acid, the active ingredient in Maxipirin, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It provides analgesic, antipyretic, anti‑inflammatory and antiplatelet effects for adult patients who need pain relief, fever reduction, inflammation control or cardiovascular event prophylaxis.

GNH USA supplies Maxipirin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Acetylsalicylic Acid works across several therapeutic areas by inhibiting prostaglandin synthesis, making it useful for the following conditions: - Pain: relief of mild to moderate nociceptive pain such as headache, musculoskeletal aches, and dental pain. - Fever: reduction of elevated body temperature associated with infection or inflammation. - Inflammation: control of inflammatory processes in conditions like arthritis. - Cardiovascular event prophylaxis: prevention of platelet aggregation to reduce the risk of myocardial infarction and stroke in at‑risk adults.

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Dyspepsia: mild stomach discomfort or indigestion. - Nausea: feeling of queasiness often without vomiting. - Abdominal pain: intermittent cramping or tenderness. - Headache: mild to moderate head pain. - Tinnitus: ringing or buzzing in the ears, usually transient.

Serious or Rare Side Effects: - Gastrointestinal ulcer: erosion of the stomach or intestinal lining. - Gastrointestinal bleeding: visible blood in stool or vomiting of blood. - Hemorrhagic stroke: bleeding within the brain. - Severe allergic reaction: rash, swelling, or anaphylaxis. - Renal impairment: reduced kidney function, especially with prolonged use.

Before using Maxipirin, consider the following safety measures: - Contraindication: avoid in patients with known hypersensitivity to aspirin or other NSAIDs. - Bleeding risk: assess for active ulcers, bleeding disorders, or concurrent anticoagulant therapy. - Reye's syndrome: do not give to children or teenagers with viral infections. - Asthma: use with caution in patients with aspirin‑exacerbated respiratory disease. - Renal/hepatic impairment: monitor function in patients with existing kidney or liver disease. - Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Acetylsalicylic Acid can interact with several medicines, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of severe bleeding. - Other NSAIDs (e.g., ibuprofen, naproxen): additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency. - Corticosteroids: synergistic risk of gastrointestinal ulceration. - Alcohol: potentiates gastric irritation and bleeding.

Moderate Interactions (Monitor Closely): - Antihypertensives (e.g., ACE inhibitors, beta‑blockers): may reduce blood‑pressure‑lowering effect. - Lithium: aspirin can raise serum lithium levels. - Methotrexate: reduced renal clearance may increase toxicity. - Diuretics: possible reduction in renal perfusion. - Oral hypoglycemics: aspirin may enhance glucose‑lowering effect.