Maxalt

Rizatriptan, the active ingredient in Maxalt, is a triptan presented as a tablet for oral use. It treats acute migraine attacks in adults, providing relief from headache and associated symptoms. GNH USA supplies Maxalt as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Maxalt is a triptan medication that targets migraine pathways to relieve acute attacks.

Migraine attack: rapid reduction of headache intensity and associated nausea or photophobia. Migraine with aura: alleviation of aura‑related discomfort and subsequent headache. Recurrent migraine: a second dose may be taken if the headache returns after initial relief.

Common Side Effects: - Nausea - Dizziness - Fatigue - Dry mouth - Tingling or numbness in fingers or toes - Chest discomfort or tightness

Serious or Rare Side Effects: - Coronary artery spasm or myocardial infarction - Stroke or transient ischemic attack - Severe hypertension - Serotonin syndrome - Anaphylactic or severe allergic reaction - Severe hepatic dysfunction

Before using Maxalt, consider the following precautions: - Cardiovascular assessment: evaluate for coronary artery disease or uncontrolled hypertension. - Drug interactions: avoid concomitant use with MAO inhibitors or other serotonergic agents. - Migraine subtype: do not use in patients with hemiplegic or basilar migraine. - Age considerations: safety in pediatric or geriatric populations has not been established. - Pregnancy and lactation: discuss potential risks with a healthcare professional. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Rizatriptan may interact with several drug classes.

Major Interactions (Avoid): - MAO inhibitors: increased risk of serotonin syndrome. - SSRIs, SNRIs, or other serotonergic agents: potential for serotonin toxicity. - Ergot alkaloids: additive vasoconstrictive effects. - Other triptans: cumulative vasoconstriction risk. - Strong CYP3A4 inhibitors (e.g., ketoconazole): elevated plasma levels.

Moderate Interactions (Monitor Closely): - NSAIDs: may increase risk of gastrointestinal bleeding. - Antihypertensives: possible additive blood pressure effects. - Oral contraceptives: may alter drug metabolism. - Antihistamines: potential for enhanced central nervous system effects. - Alcohol: may exacerbate dizziness and drowsiness.