GNH USA

Europe — EMA

Mastical D

GNH USA supplies Mastical D (Colecalciferol), a vitamin D and calcium supplement for bone health and calcium deficiency. Request a quote for global supply.

Colecalciferol, Calcium

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What is Colecalciferol, Calcium?

Colecalciferol, the active ingredient in Mastical D, is a vitamin D and calcium supplement presented as an oral tablet for oral use. It supports bone mineralization and helps correct vitamin D and calcium deficiencies in children and adults, particularly for individuals at risk of osteoporosis or low bone mass.

GNH USA supplies Mastical D as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

What is Colecalciferol, Calcium used for?

Mastical D provides vitamin D3 and calcium to address conditions related to bone health and mineral deficiency.

- Osteoporosis: helps maintain bone density and reduces fracture risk. - Vitamin D deficiency: restores normal serum 25‑hydroxyvitamin D levels. - Hypocalcemia: supports normal calcium concentrations in blood. - Rickets: assists bone mineralization in children with deficient vitamin D and calcium.

What are the side effects of Colecalciferol, Calcium?

Mastical D may cause adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea - Constipation - Abdominal discomfort - Headache - Dry mouth - Mild hypercalcemia (elevated calcium levels)

Serious or Rare Side Effects: - Severe hypercalcemia leading to kidney stones or cardiac arrhythmia - Hypervitaminosis D with systemic toxicity - Allergic reactions such as rash, pruritus or angioedema - Calcification of soft tissues (e.g., blood vessels) - Acute renal failure in extreme cases

What precautions apply to Colecalciferol, Calcium?

Before using Mastical D, consider the following safety measures.

- Baseline assessment: evaluate serum calcium and 25‑hydroxyvitamin D levels. - Renal monitoring: check kidney function periodically, especially in patients with renal impairment. - Concomitant supplements: avoid taking additional high‑dose calcium or vitamin D without medical advice. - Specific conditions: use cautiously in sarcoidosis, granulomatous diseases, or hyperparathyroidism. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original container, protect from moisture and light.

What does Colecalciferol, Calcium interact with?

Mastical D can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid): - Thiazide diuretics: increase risk of hypercalcemia. - High‑dose vitamin A: may precipitate hypervitaminosis D. - Lithium: can raise calcium levels.

Moderate Interactions (Monitor Closely): - Corticosteroids: may reduce calcium absorption. - Anticonvulsants (e.g., phenytoin, phenobarbital): accelerate vitamin D metabolism. - Orlistat: may decrease absorption of fat‑soluble vitamins including vitamin D.

Frequently asked questions

What is Mastical D used for?+
Mastical D is a nutritional supplement that provides vitamin D3 (colecalciferol) and calcium. It is used to correct vitamin D and calcium deficiencies, support bone mineralization, and help manage conditions such as osteoporosis, hypocalcemia, and rickets under medical supervision.
How does colecalciferol work in the body?+
Colecalciferol is converted first to 25‑hydroxyvitamin D in the liver and then to the active hormone 1,25‑dihydroxyvitamin D in the kidney. This active form binds to vitamin D receptors, enhancing the expression of calcium‑binding proteins in the intestine, which increases calcium absorption and promotes bone mineralization.
What is the usual dose of Mastical D?+
The appropriate dose of Mastical D is determined by a prescriber based on the patient’s age, clinical condition, baseline vitamin D and calcium levels, and any concurrent therapies. Patients should follow the specific dosing instructions provided by their healthcare professional.
Is Mastical D safe during pregnancy or breastfeeding?+
Pregnant or breastfeeding individuals should only use Mastical D after consulting a healthcare professional. Vitamin D and calcium are essential nutrients during these periods, but dosing must be individualized to avoid excess intake that could affect maternal or fetal health.
How do I order Mastical D from GNH USA?+
To place an order, submit an enquiry on the Mastical D product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.
How does Mastical D compare with other vitamin D supplements?+
Mastical D combines both colecalciferol (vitamin D3) and elemental calcium in a single oral tablet, whereas many vitamin D products contain only the vitamin. This dual formulation can simplify therapy for patients who need both nutrients, but clinicians may choose separate products based on individual dosing requirements or specific patient conditions.
What are the storage and handling requirements for Mastical D?+
Mastical D should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability throughout its shelf life.
How is Mastical D administered?+
Mastical D is taken orally, usually with water. The tablet should be swallowed whole and not chewed or crushed unless a healthcare professional advises otherwise. It can be taken with or without food, but consistent administration with meals may improve calcium absorption.
What are the most serious risks associated with Mastical D?+
The most serious risks include severe hypercalcemia, which can lead to kidney stones, cardiac arrhythmias, or soft‑tissue calcification, and hypervitaminosis D, which may cause nausea, vomiting, weakness, and in extreme cases, renal failure. Patients should be monitored for symptoms and have serum calcium checked regularly.
Who should not use Mastical D?+
Mastical D should be avoided in individuals with known hypersensitivity to colecalciferol, calcium, or any excipients, as well as patients with untreated hypercalcemia, severe renal impairment, or conditions such as sarcoidosis where vitamin D metabolism is altered, unless a physician determines it is appropriate.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Colecalciferol, Calcium
Route
Oral Use
Manufacturer
Cheplapharm Arzneimittel Gmbh
Origin
EU

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