Mastical D (Colecalciferol, Calcium)

Colecalciferol, the active ingredient in Mastical D, is a vitamin D and calcium supplement presented as an oral tablet for oral use. It supports bone mineralization and helps correct vitamin D and calcium deficiencies in children and adults, particularly for individuals at risk of osteoporosis or low bone mass.

GNH USA supplies Mastical D as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

Mastical D provides vitamin D3 and calcium to address conditions related to bone health and mineral deficiency.

- Osteoporosis: helps maintain bone density and reduces fracture risk. - Vitamin D deficiency: restores normal serum 25‑hydroxyvitamin D levels. - Hypocalcemia: supports normal calcium concentrations in blood. - Rickets: assists bone mineralization in children with deficient vitamin D and calcium.

Mastical D may cause adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea - Constipation - Abdominal discomfort - Headache - Dry mouth - Mild hypercalcemia (elevated calcium levels)

Serious or Rare Side Effects: - Severe hypercalcemia leading to kidney stones or cardiac arrhythmia - Hypervitaminosis D with systemic toxicity - Allergic reactions such as rash, pruritus or angioedema - Calcification of soft tissues (e.g., blood vessels) - Acute renal failure in extreme cases

Before using Mastical D, consider the following safety measures.

- Baseline assessment: evaluate serum calcium and 25‑hydroxyvitamin D levels. - Renal monitoring: check kidney function periodically, especially in patients with renal impairment. - Concomitant supplements: avoid taking additional high‑dose calcium or vitamin D without medical advice. - Specific conditions: use cautiously in sarcoidosis, granulomatous diseases, or hyperparathyroidism. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original container, protect from moisture and light.

Mastical D can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid): - Thiazide diuretics: increase risk of hypercalcemia. - High‑dose vitamin A: may precipitate hypervitaminosis D. - Lithium: can raise calcium levels.

Moderate Interactions (Monitor Closely): - Corticosteroids: may reduce calcium absorption. - Anticonvulsants (e.g., phenytoin, phenobarbital): accelerate vitamin D metabolism. - Orlistat: may decrease absorption of fat‑soluble vitamins including vitamin D.