Mastical

Calcium carbonate, the active ingredient in Mastical, is a calcium supplement presented as an oral tablet for oral use. It helps replenish calcium stores and supports normal bone mineralization in adults and children who require additional calcium, contributing to skeletal health and various calcium‑dependent metabolic processes.

GNH USA supplies Mastical as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU quality standards and is available for bulk and retail distribution. GNH USA also provides regulatory support and customized packaging options to meet client requirements.

Mastical (calcium carbonate) is used as a calcium supplement to address conditions associated with low calcium intake or increased calcium demand. - Calcium deficiency: helps restore normal serum calcium levels and supports bone health. - Osteopenia prevention: provides supplemental calcium to aid in maintaining bone mineral density. - Post‑menopausal bone health: contributes to calcium intake needed for reducing bone loss in post‑menopausal women.

Calcium carbonate is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects: - Constipation: mild bowel slowdown leading to hard stools. - Flatulence: increased gas production causing abdominal discomfort. - Nausea: feeling of queasiness or urge to vomit.

Serious or Rare Side Effects: - Hypercalcemia: elevated blood calcium that can cause weakness, confusion, or cardiac arrhythmia. - Kidney stones: formation of calcium‑containing calculi in susceptible individuals. - Allergic reaction: rash, itching, swelling, or difficulty breathing.

When using Mastical, consider the following precautions to ensure safe and effective use. - Assess calcium intake: evaluate dietary calcium to avoid excess supplementation. - Monitor renal function: patients with kidney disease should have calcium levels checked regularly. - Review concomitant medications: certain drugs (e.g., thiazides, vitamin D analogues) may increase calcium load. - Pregnancy and lactation: use only under medical supervision as calcium needs differ. - Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Calcium carbonate can interact with several medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid): - Bisphosphonates: calcium can reduce absorption of bisphosphonate tablets; separate dosing by at least 2 hours. - Tetracycline antibiotics: calcium chelates tetracyclines, decreasing their effectiveness. - Iron supplements: concurrent intake may impair absorption of both agents.

Moderate Interactions (Monitor Closely): - Thiazide diuretics: may increase risk of hypercalcemia; monitor serum calcium. - Vitamin D analogues: combined use can raise calcium levels; adjust dosage as needed. - Levothyroxine: calcium may interfere with absorption; separate administration times.