GNH USA

Europe — EMA

Massido (Nebivolol)

GNH USA supplies Massido (Nebivolol), a selective β1‑blocker indicated for hypertension. Request a quote for worldwide pharmaceutical supply to global

Nebivolol

Request sourcing

1
Pack/s

What is Nebivolol?

Nebivolol, the active ingredient in Massido, is a beta blocker presented as a tablet for oral use. It treats hypertension in adult patients. GNH USA supplies Massido as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Nebivolol used for?

Nebivolol is indicated for the management of high blood pressure, acting on the cardiovascular system to lower systemic pressure.

Hypertension: reduces systolic and diastolic blood pressure in patients with essential hypertension.

What are the side effects of Nebivolol?

Nebivolol may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects: - Headache: mild to moderate pain in the head. - Dizziness: sensation of light‑headedness, especially on standing. - Fatigue: feeling unusually tired or weak. - Nausea: upset stomach or urge to vomit. - Bradycardia: slower than normal heart rate. - Peripheral edema: swelling of the ankles or feet.

Serious or Rare Side Effects: - Severe bradycardia: markedly low heart rate requiring medical attention. - Symptomatic hypotension: dangerously low blood pressure causing faintness. - Acute heart failure exacerbation: worsening of cardiac function. - Allergic reactions: rash, itching, swelling, or anaphylaxis. - Liver injury: abnormal liver function tests or jaundice. - Bronchospasm: narrowing of airways, especially in patients with asthma.

What precautions apply to Nebivolol?

Nebivolol requires careful monitoring and specific safety measures before and during therapy. - Blood pressure monitoring: check regularly to ensure therapeutic targets are met. - Hepatic impairment: use cautiously in patients with severe liver disease. - Abrupt discontinuation: taper dose to avoid rebound hypertension. - Respiratory conditions: avoid in uncontrolled asthma or severe COPD. - Drug interactions: review concomitant medications for potential additive effects. - Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and light.

What does Nebivolol interact with?

Nebivolol can interact with several medicines, influencing its efficacy or safety.

Major Interactions (Avoid): - Other β‑blockers: may cause excessive bradycardia or hypotension. - Calcium‑channel blockers (verapamil, diltiazem): increase nebivolol plasma levels. - CYP2D6 inhibitors (paroxetine, fluoxetine): raise nebivolol concentrations. - Insulin or sulfonylureas: mask hypoglycaemic symptoms. - Antihypertensive combinations: risk of additive blood‑pressure lowering.

Moderate Interactions (Monitor Closely): - NSAIDs: may reduce antihypertensive effect. - Diuretics: monitor electrolytes and renal function. - Antidepressants (sertraline): observe for heart‑rate changes. - Antidiabetic agents: watch for altered glucose control. - Lipid‑lowering drugs (statins): assess for rare muscle toxicity.

Frequently asked questions

What is Massido used for?+
Massido contains nebivolol, which is prescribed to lower high blood pressure in adults. By reducing systemic vascular resistance and heart rate, it helps achieve target blood‑pressure levels and lowers the risk of cardiovascular complications associated with hypertension.
How does nebivolol work?+
Nebivolol selectively blocks β1‑adrenergic receptors in the heart, decreasing heart rate and contractility. It also stimulates endothelial nitric oxide release, causing vasodilation. The combined effect reduces cardiac output and peripheral resistance, resulting in lower arterial pressure.
What is the usual dose of Massido?+
The dosage of Massido is individualized by a qualified prescriber based on the patient’s clinical condition, blood‑pressure response, and tolerability. The prescribing physician determines the appropriate strength, frequency, and any titration schedule.
Is Massido safe during pregnancy or breastfeeding?+
Nebivolol is generally classified as a pregnancy‑category drug with limited safety data. It should only be used if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult their healthcare provider, as the drug may be excreted in milk.
How do I order Massido from GNH USA?+
To request Massido, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.
How does Massido compare with other antihypertensive drugs?+
Nebivolol offers a unique combination of β1‑blockade and nitric‑oxide‑mediated vasodilation, which can provide better tolerability and fewer metabolic side effects compared with traditional non‑selective β‑blockers. It is often considered alongside ACE inhibitors, ARBs, or calcium‑channel blockers based on patient profile.
What are the storage and handling requirements for Massido?+
Massido tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date indicated on the label.
How is Massido administered?+
Massido is taken orally, usually with or without food, as directed by the prescribing clinician. Swallow the tablet whole with a glass of water and follow the dosing schedule provided on the prescription label.
What are the most serious risks associated with Massido?+
Serious risks include severe bradycardia, symptomatic hypotension, acute heart‑failure exacerbation, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience fainting, rapid weight gain, swelling, or signs of an allergic response.
Who should not use Massido?+
Massido is contraindicated in patients with known hypersensitivity to nebivolol or any excipients, those with severe bradycardia, second‑ or third‑degree atrioventricular block without a pacemaker, and individuals in cardiogenic shock. Caution is also advised for patients with uncontrolled asthma or severe COPD.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Nebivolol
Route
Oral Use
Manufacturer
Alkaloid-Int D.O.O.
Origin
EU

Related products

Nebivolol 20 mg/1

Nebivolol 20 mg/1

Nebivolol · 20 mg

nebivolol
TABLET
Major Pharmaceuticals
USA
NEBIVOLOL 2.5 mg/1

NEBIVOLOL 2.5 mg/1

Nebivolol · 2.5 mg

Nebivolol
TABLET
Major Pharmaceuticals
USA
NEBIVOLOL 5 mg/1

NEBIVOLOL 5 mg/1

Nebivolol · 5 mg

Nebivolol
TABLET
Major Pharmaceuticals
USA
NEBIVOLOL 10 mg/1

NEBIVOLOL 10 mg/1

Nebivolol · 10 mg

Nebivolol
TABLET
Major Pharmaceuticals
USA