Margot

Drospirenone and ethinylestradiol, the active ingredients in Margot, are a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy in women of reproductive age.

GNH USA supplies Margot as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Margot, a combined oral contraceptive, is used to prevent pregnancy by suppressing ovulation.

- Prevention of pregnancy: provides reliable contraception for women of childbearing age. - Management of menstrual-related symptoms: helps regulate menstrual cycles and reduce dysmenorrhea. - Treatment of acne: may improve acne associated with androgen excess.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Breast tenderness: discomfort or swelling of the breasts. - Headache: occasional throbbing pain. - Weight gain: modest increase in body weight. - Mood changes: irritability or mood swings. - Spotting: irregular vaginal bleeding.

Serious or Rare Side Effects: - Venous thromboembolism: blood clots in deep veins. - Arterial thrombosis: clot formation in arteries, potentially leading to stroke. - Hypertension: elevated blood pressure. - Liver disorders: jaundice or hepatic dysfunction. - Gallbladder disease: gallstones or cholecystitis. - Severe allergic reactions: rash, swelling, or anaphylaxis.

Before using Margot, consider the following precautions: - Pregnancy: contraindicated; do not use if pregnant. - Smoking: avoid if over 35 years and smoking >15 cigarettes per day. - Thromboembolic history: avoid if personal or family history of blood clots. - Liver disease: use with caution in hepatic impairment. - Hypertension: monitor blood pressure regularly. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Margot may interact with several medicines.

Major Interactions (Avoid): - CYP3A4 inducers (e.g., rifampin, carbamazepine): reduce contraceptive effectiveness. - Antifungal agents (e.g., ketoconazole): increase hormone levels, risk of side effects. - St. John’s wort: may diminish contraceptive efficacy.

Moderate Interactions (Monitor Closely): - Antidepressants (SSRIs): may increase risk of mood changes. - Anticonvulsants (phenytoin): may alter hormone metabolism. - Antihypertensives: monitor blood pressure for additive effects. - Herbal supplements (ginkgo): potential platelet effects. - Diuretics: may affect electrolyte balance.