Maratia (Tramadol Hydrochloride, Paracetamol)

Tramadol Hydrochloride, the active ingredient in Maratia, is a combination analgesic presented as an oral tablet for oral use. It provides pain relief for moderate to severe acute pain, including postoperative and musculoskeletal pain, by acting on central nervous system pathways.

GNH USA supplies Maratia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and regulatory requirements. The company ensures batch traceability and on‑time delivery to meet global healthcare needs.

Maratia, a combination analgesic containing tramadol and paracetamol, is used to manage pain in several clinical situations.

- Moderate to severe acute pain: provides effective analgesia when non‑opioid agents are insufficient. - Postoperative pain: reduces pain intensity after surgical procedures, facilitating recovery. - Musculoskeletal pain: alleviates pain associated with injuries or inflammatory conditions of muscles and joints.

Maratia may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea: mild stomach upset often occurring early in therapy. - Dizziness: transient light‑headedness or vertigo. - Constipation: reduced bowel movements. - Headache: mild to moderate cranial pain.

Serious or Rare Side Effects: - Respiratory depression: slowed breathing, especially at high doses or with other depressants. - Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.

When prescribing Maratia, consider the following precautions.

- Assess renal and hepatic function: adjust use in patients with impairment. - Avoid in patients with known hypersensitivity to tramadol or paracetamol. - Use caution with concomitant CNS depressants: increased sedation risk. - Monitor for signs of dependence or misuse: especially with prolonged therapy. - Pregnancy and breastfeeding: evaluate risk‑benefit before prescribing. - Store at ambient temperature: keep in original container, protect from moisture and heat.

Maratia can interact with several medicines; awareness of the level of interaction helps guide safe use.

Major Interactions (Avoid): - MAO inhibitors: risk of serotonin syndrome. - CNS depressants (e.g., benzodiazepines, alcohol): additive sedation and respiratory depression. - CYP2D6 inhibitors (e.g., quinidine): may increase tramadol plasma concentrations.

Moderate Interactions (Monitor Closely): - Serotonergic drugs (SSRIs, SNRIs): potential for serotonin syndrome. - Anticoagulants (warfarin): paracetamol may enhance bleeding risk. - Anticonvulsants (carbamazepine): may reduce tramadol efficacy.