GNH USA

Europe — EMA

Mann

GNH USA supplies Mann (Paracetamol and Caffeine), an analgesic for pain, headache and fever. Product for healthcare providers. Request a quote for supply.

Paracetamol, Caffeine

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What is Paracetamol, Caffeine?

Paracetamol and Caffeine, the active ingredients in Mann, are an analgesic and a central nervous system stimulant presented as an oral tablet for oral use. The combination provides pain relief, reduces fever and alleviates headache in adults and children, with caffeine enhancing the analgesic effect of paracetamol.

GNH USA supplies Mann as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide. The company ensures batch traceability, regulatory compliance and reliable logistics for global distribution.

What is Paracetamol, Caffeine used for?

Mann, containing paracetamol and caffeine, is used for the symptomatic relief of pain and fever. - Pain: provides analgesic relief for mild to moderate pain. - Headache: reduces intensity of tension‑type or migraine‑associated headache. - Fever: lowers elevated body temperature in febrile conditions.

What are the side effects of Paracetamol, Caffeine?

Paracetamol and caffeine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea: mild stomach upset that may occur after dosing. - Insomnia: difficulty sleeping due to caffeine’s stimulant effect. - Restlessness: feeling of agitation or increased nervousness. - Dizziness: transient light‑headedness in some individuals. - Increased heart rate: mild tachycardia related to caffeine.

Serious or Rare Side Effects: - Allergic reactions: rash, itching, swelling or anaphylaxis. - Liver toxicity: rare but possible hepatic injury with overdose. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

What precautions apply to Paracetamol, Caffeine?

When using Mann, consider the following precautions to ensure safe use. - Assess liver function: avoid in patients with severe hepatic impairment. - Limit total caffeine intake: consider caffeine from other sources to prevent excess stimulation. - Avoid use in infants under 12 months: safety not established for this age group. - Consult healthcare professional if pregnant or breastfeeding: safety data are limited. - Do not exceed recommended daily dose: risk of hepatotoxicity increases with overdose. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Paracetamol, Caffeine interact with?

Mann may interact with other medicines; notable interactions include:

Major Interactions (Avoid): - Warfarin: increased anticoagulant effect may raise bleeding risk. - Carbamazepine: enzyme induction can reduce paracetamol efficacy. - Monoamine oxidase inhibitors: combined with caffeine may cause hypertensive episodes.

Moderate Interactions (Monitor Closely): - Alcohol: concurrent use can enhance liver toxicity. - Other CNS stimulants: additive stimulant effects may cause nervousness. - Diuretics: may increase caffeine clearance, reducing its effect.

Frequently asked questions

What is Mann used for?+
Mann is an over‑the‑counter oral tablet that combines paracetamol and caffeine to provide symptomatic relief of mild to moderate pain, headache and fever. The caffeine component enhances the analgesic effect of paracetamol, making the product useful for adults and children who need rapid, short‑term relief of these common conditions.
How does paracetamol and caffeine work in Mann?+
Paracetamol works by centrally inhibiting cyclooxygenase enzymes, which reduces prostaglandin production and therefore lowers pain perception and body temperature. Caffeine blocks adenosine receptors in the brain, producing a stimulant effect and increasing alertness. This antagonism also amplifies the pain‑relieving action of paracetamol, resulting in a more pronounced analgesic response.
What is the usual dose of Mann?+
The appropriate dose of Mann is determined by a qualified healthcare professional based on the individual’s age, weight, clinical condition and any other medications being taken. Prescribers follow local guidelines for paracetamol‑caffeine combinations and adjust the regimen to achieve effective symptom control while minimizing risk.
Is Mann safe during pregnancy or breastfeeding?+
Safety data for the combined use of paracetamol and caffeine during pregnancy or lactation are limited. Paracetamol alone is generally considered low‑risk when used at recommended doses, but caffeine crosses the placenta and is excreted in breast milk. Women who are pregnant or breastfeeding should consult their healthcare provider before using Mann.
How do I order Mann from GNH USA?+
To place an order, submit an enquiry on the Mann product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.
How does Mann compare with other analgesic options?+
Mann combines paracetamol with caffeine, offering a synergistic effect that can be more effective for certain headaches and mild pain than paracetamol alone. Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen, Mann does not carry the same gastrointestinal or cardiovascular risks, but it also lacks anti‑inflammatory activity. Choice of therapy depends on the patient’s medical history and specific symptom profile.
How should Mann be stored and handled?+
Mann tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments. Do not use the tablets after the expiry date printed on the pack.
How is Mann administered?+
Mann is taken orally with a glass of water. The tablet should be swallowed whole; it is not intended to be chewed, crushed or dissolved. Patients should follow the dosing instructions provided by their prescriber or the product label, and should not exceed the maximum daily amount of paracetamol contained in the combination.
What are the most serious risks to watch for when using Mann?+
The most serious risks include severe allergic reactions such as rash, swelling or anaphylaxis, and rare cases of liver toxicity, especially when the recommended maximum daily dose of paracetamol is exceeded. Patients should seek immediate medical attention if they notice signs of a serious skin reaction, persistent nausea, jaundice, or any symptoms suggestive of an allergic response.
Who should not use Mann?+
Mann should be avoided by individuals with known hypersensitivity to paracetamol, caffeine or any excipients in the tablet. It is also contraindicated in patients with severe hepatic impairment, uncontrolled hypertension, or those taking monoamine oxid
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Paracetamol, Caffeine
Route
Oral Use
Manufacturer
Laboratoires Smb S.A.
Origin
EU

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