Mallebrin

Aluminium Chloride Hexahydrate, the active ingredient in Mallebrin, is an aluminium salt (astringent) presented as a topical preparation for oromucosal use. It is employed to reduce excessive secretions and to provide a protective barrier on mucosal surfaces, aiding in conditions such as hyperhidrosis and oral ulcerations.

GNH USA supplies Mallebrin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and offers reliable global distribution.

Mallebrin, containing aluminium chloride hexahydrate, is used as a topical astringent for conditions involving excess secretions or mucosal irritation. - Hyperhidrosis: reduces excessive sweating on affected skin areas. - Oral aphthous ulcers: promotes healing by forming a protective protein barrier. - Minor mucosal bleeding: assists hemostasis through protein precipitation. - Dermatologic warts: facilitates lesion shrinkage by drying and astringent action. - Seborrheic dermatitis: helps control oil secretion and irritation.

Aluminium chloride hexahydrate may cause local and systemic reactions, which are categorized by frequency.

Common Side Effects: - Local burning sensation. - Stinging or tingling at the application site. - Dryness of the treated area. - Transient taste alteration. - Mild irritation or erythema. - Temporary discoloration of skin or mucosa.

Serious or Rare Side Effects: - Allergic contact dermatitis. - Severe skin ulceration. - Systemic aluminium toxicity (rare with extensive use). - Anaphylactic reaction. - Persistent mucosal ulceration. - Methemoglobinemia (very rare).

Before using Mallebrin, consider the following safety measures. - Avoid application on broken or inflamed mucosa: may increase irritation. - Limit frequency of use: excessive application can cause dryness. - Assess for aluminium allergy: discontinue if hypersensitivity occurs. - Use with caution in renal impairment: reduced aluminium clearance. - Consult a healthcare professional before use in pregnancy or breastfeeding. - Store at room temperature: keep in original container, protect from moisture and light.

Aluminium chloride hexahydrate can interact with certain medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Oral aluminium‑containing antacids or supplements: risk of aluminium overload and toxicity. - Iron or calcium supplements taken simultaneously: may reduce aluminium absorption and alter efficacy.

Moderate Interactions (Monitor Closely): - Topical corticosteroids applied to the same area: may increase local irritation. - Other astringent agents (e.g., zinc chloride): additive drying effect. - Systemic antibiotics affecting oral flora: possible alteration of normal microbiome.