Malina

Desogestrel, the active ingredient in Malina, is a progestin presented as a tablet for oral use. It provides hormonal contraception by preventing ovulation and creating cervical mucus changes that inhibit fertilization in women of reproductive age.

GNH USA supplies Malina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Desogestrel is a progestin‑only oral contraceptive that acts within the reproductive hormone pathway to prevent pregnancy.

Contraception: provides reliable birth control for women of childbearing potential. Ovulation inhibition: suppresses the luteinizing hormone surge to prevent egg release. Cervical mucus alteration: thickens mucus to reduce sperm penetration.

Desogestrel may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Irregular vaginal bleeding or spotting - Headache - Nausea or abdominal discomfort - Breast tenderness - Weight gain or fluid retention - Mood changes or irritability

Serious or Rare Side Effects: - Deep vein thrombosis or pulmonary embolism - Hepatic adenoma or other liver abnormalities - Severe hypertension - Allergic reaction, including anaphylaxis - Visual disturbances or eye problems - Persistent severe abdominal pain

Before initiating therapy, consider the following safety measures.

Contraindicated in pregnancy: category X; avoid use during pregnancy. Active thromboembolic disease: do not use in patients with current clotting disorders. Smoking over age 35: increased risk of cardiovascular events; advise cessation. Liver disease: monitor hepatic function and avoid in severe impairment. Blood pressure monitoring: check regularly, especially in hypertensive patients. Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Desogestrel can interact with several medicines, affecting its contraceptive efficacy.

Major Interactions (Avoid): - Enzyme‑inducing antiepileptics (e.g., carbamazepine, phenytoin): markedly reduce plasma levels. - Rifampin or other strong inducers: decrease effectiveness of contraception. - St. John’s wort: may lower contraceptive reliability.

Moderate Interactions (Monitor Closely): - Azole antifungals (e.g., ketoconazole): may increase desogestrel concentrations. - Protease inhibitor antiretrovirals: potential alteration of metabolism. - Certain antibiotics (e.g., tetracycline): possible reduced contraceptive effect, though clinical significance is uncertain.