Makro-Albumon (Human Serum Albumin)

Human Serum Albumin, the active ingredient in Makro-Albumon, is a plasma volume expander presented as a sterile injectable solution for intravenous use. It is employed to increase circulating plasma volume in patients with hypovolemia, severe burns, hypoalbuminemia, and other conditions requiring rapid oncotic support.

GNH USA supplies Makro-Albumon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide.

Makro-Albumon is a human serum albumin product used in clinical situations that require rapid plasma volume expansion and restoration of oncotic pressure. - Hypovolemia: restores intravascular volume and improves tissue perfusion. - Severe burns: supports plasma oncotic pressure and reduces edema. - Hypoalbuminemia: raises serum albumin concentrations to normal levels. - Cardiac surgery: maintains hemodynamic stability during peri‑operative fluid management.

Human Serum Albumin may be associated with a range of adverse reactions, most of which are related to infusion or immune response.

Common Side Effects: - Fever or chills during infusion. - Mild rash or urticaria. - Transient hypotension. - Headache. - Nausea or vomiting. - Localized pain at the injection site.

Serious or Rare Side Effects: - Anaphylactic or severe allergic reaction. - Volume overload leading to pulmonary edema. - Acute renal failure. - Hemolysis. - Thrombosis or embolic events. - Severe hypertension.

When using Makro-Albumon, clinicians should observe several safety measures to minimize risk. - Assess fluid status: avoid excessive volume that could cause overload. - Monitor serum albumin levels: adjust dosing based on laboratory results. - Check for allergy: discontinue immediately if signs of hypersensitivity appear. - Use caution in cardiac failure: patients are prone to volume‑related complications. - Avoid in patients with known hypersensitivity to human albumin preparations. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Human Serum Albumin can interact with other agents that affect fluid balance or coagulation.

Major Interactions (Avoid): - Concurrent high‑dose diuretics: may worsen intravascular depletion. - Vasopressor therapy: can mask hypotensive responses. - Incompatible plasma products: risk of immune reactions.

Moderate Interactions (Monitor Closely): - Synthetic colloids (e.g., hydroxyethyl starch): additive volume effect. - Renal replacement therapy: may alter albumin clearance. - Anticoagulants: monitor for altered bleeding risk.