GNH USA

Europe — EMA

Maexeni

GNH USA supplies Maexeni (Ethinylestradiol/Levonorgestrel), a combined oral contraceptive for prevention of pregnancy. Request a quote for global supply.

Ethinylestradiol, Levonorgestrel

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What is Ethinylestradiol, Levonorgestrel?

Ethinylestradiol and Levonorgestrel, the active ingredients in Maexeni, are a combined oral contraceptive presented as a tablet for oral use. They work together to prevent pregnancy by inhibiting ovulation and altering cervical mucus and the endometrium. GNH USA supplies Maexeni as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ethinylestradiol, Levonorgestrel used for?

Maexeni, a combined oral contraceptive, is indicated for hormonal contraception to prevent pregnancy. - Contraception: prevents pregnancy by suppressing ovulation and modifying cervical mucus. - Family planning: provides reliable birth control for women of reproductive age. - Menstrual cycle regulation: helps achieve more predictable bleeding patterns and reduces menstrual discomfort.

What are the side effects of Ethinylestradiol, Levonorgestrel?

Common Side Effects: - Nausea: mild to moderate stomach upset. - Breast tenderness: temporary swelling or discomfort. - Headache: occasional tension‑type headaches. - Spotting or breakthrough bleeding: irregular light bleeding. - Mood changes: irritability or mild mood swings. - Weight fluctuation: slight increase or fluid retention.

Serious or Rare Side Effects: - Deep vein thrombosis: blood clot formation in veins. - Pulmonary embolism: clot migration to lung vessels. - Stroke: cerebrovascular accident due to clot or hemorrhage. - Myocardial infarction: heart attack risk, especially in smokers. - Severe allergic reaction: rash, swelling, or anaphylaxis. - Liver tumor: rare hepatic adenoma development.

What precautions apply to Ethinylestradiol, Levonorgestrel?

Before initiating Maexeni, consider the following precautions. - Cardiovascular assessment: evaluate risk factors such as hypertension, smoking, or clotting disorders. - Liver function: avoid use in patients with active liver disease or severe hepatic impairment. - Smoking status: advise women over 35 who smoke to discontinue use. - Missed dose management: provide clear instructions for handling forgotten tablets. - Concomitant medications: review other drugs that may affect efficacy or safety. - Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture and direct sunlight.

What does Ethinylestradiol, Levonorgestrel interact with?

Maexeni may interact with several medicines that alter its effectiveness or safety. Major Interactions (Avoid): - CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin): markedly reduce contraceptive efficacy. - St. John’s wort: may decrease hormone levels, leading to breakthrough bleeding. - Certain antiepileptics (e.g., phenobarbital): lower plasma concentrations of the active ingredients.

Moderate Interactions (Monitor Closely): - Antifungals (e.g., ketoconazole, itraconazole): may increase hormone levels, raising side‑effect risk. - HIV protease inhibitors (e.g., ritonavir): can elevate plasma concentrations. - Selective serotonin reuptake inhibitors (e.g., fluoxetine): may modestly affect hormone metabolism. - Diuretics and antihypertensives: monitor blood pressure as hormonal changes can influence fluid balance.

Frequently asked questions

What is Maexeni used for?+
Maexeni is a combined oral contraceptive containing ethynylestradiol and levonorgestrel. It is prescribed to prevent pregnancy by inhibiting ovulation and altering cervical mucus, providing reliable hormonal birth control for women of reproductive age.
How does ethynylestradiol work in Maexeni?+
Ethynylestradiol, the estrogen component, binds to estrogen receptors and suppresses the release of follicle‑stimulating hormone (FSH). This helps regulate the menstrual cycle and works together with levonorgestrel to prevent the surge of luteinising hormone (LH) that triggers ovulation.
What is the usual dose of Maexeni?+
The dosing regimen for Maexeni is determined by the prescribing healthcare professional. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and any variations should follow the prescriber’s instructions.
Is Maexeni safe to use during pregnancy or breastfeeding?+
Maexeni is intended for use before pregnancy and should be discontinued if pregnancy occurs. It is not recommended during pregnancy. Limited data are available for breastfeeding; women should discuss risks and benefits with their healthcare provider before using it while nursing.
How do I order Maexeni from GNH USA?+
To order Maexeni, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.
How does Maexeni compare with other combined oral contraceptives?+
Maexeni contains the standard dose combination of ethynylestradiol and levonorgestrel, a widely used progestin. Its efficacy and safety profile are comparable to other combined oral contraceptives that use the same hormone pair, while formulation differences may affect tolerability for individual patients.
What are the storage requirements for Maexeni?+
Maexeni tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.
How is Maexeni administered?+
Maexeni is taken orally as a tablet. The usual instruction is to swallow one tablet with water each day, preferably at the same time, without crushing or chewing, to maintain consistent hormone levels.
What are the most serious risks associated with Maexeni?+
Serious risks include venous thromboembolism (deep‑vein thrombosis, pulmonary embolism), arterial events such as stroke or myocardial infarction, and rare liver tumors. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should be evaluated carefully before use.
Who should not use Maexeni?+
Maexeni is contraindicated in women with known or suspected pregnancy, active liver disease, a history of thromboembolic disorders, uncontrolled hypertension, breast cancer, or those who are smokers over 35 years old. It should also be avoided in individuals with known hypersensitivity to any component of the tablet.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ethinylestradiol, Levonorgestrel
Route
Oral Use
Manufacturer
Hormosan Pharma Gmbh
Origin
EU

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