Europe — EMA
Madopark Quick (Benserazide Hydrochloride, Levodopa)
GNH USA supplies Madopark Quick (Levodopa/Benserazide), a dopamine precursor with dopa decarboxylase inhibitor for Parkinson's disease. Request a quote.
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What is Benserazide Hydrochloride, Levodopa?
Levodopa / Benserazide, the active ingredient in Madopark Quick, is a dopamine precursor with dopa decarboxylase inhibitor presented as an immediate‑release oral tablet for oral use. It treats Parkinson's disease in adults.
GNH USA supplies Madopark Quick as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Benserazide Hydrochloride, Levodopa used for?
Madopark Quick is indicated for the management of Parkinsonian disorders by restoring central dopamine levels.
- Parkinson's disease: Improves motor symptoms and functional ability in patients with idiopathic Parkinson's disease. - Motor fluctuations in Parkinson's disease: Reduces OFF periods and increases ON time without troublesome dyskinesia. - Drug‑induced parkinsonism: Provides symptomatic relief when anticholinergic therapy is insufficient.
What are the side effects of Benserazide Hydrochloride, Levodopa?
Common Side Effects: - Nausea: Upset stomach or feeling sick. - Orthostatic hypotension: Dizziness upon standing. - Headache: Mild to moderate head pain. - Insomnia: Difficulty falling or staying asleep. - Dyskinesia: Involuntary movements, especially at higher doses. - Dry mouth: Reduced salivation.
Serious or Rare Side Effects: - Severe hypotension: Marked drop in blood pressure requiring medical attention. - Psychosis or hallucinations: Visual or auditory disturbances. - Neuroleptic malignant syndrome: Rare but life‑threatening reaction. - Cardiac arrhythmias: Irregular heart rhythms. - Severe allergic reactions: Rash, swelling, or breathing difficulty.
What precautions apply to Benserazide Hydrochloride, Levodopa?
When prescribing Madopark Quick, clinicians should consider several safety measures. - Dose titration: Start with a low dose and increase gradually to minimize side effects. - Blood pressure monitoring: Watch for orthostatic hypotension, especially in the elderly. - Psychiatric assessment: Monitor for hallucinations, confusion, or mood changes. - Contraindications: Avoid in patients with narrow‑angle glaucoma or those taking non‑selective MAO inhibitors. - Renal/hepatic impairment: Adjust dosing based on organ function. - Store at ambient temperature: Keep in the original pack, protect from moisture.
What does Benserazide Hydrochloride, Levodopa interact with?
Madopark Quick may interact with several medicines, requiring careful management.
Major Interactions (Avoid): - Non‑selective MAO inhibitors: Risk of hypertensive crisis. - Antipsychotics (dopamine antagonists): Reduce therapeutic effect. - High‑dose pyridoxine (vitamin B6): Decreases levodopa availability.
Moderate Interactions (Monitor Closely): - Antihypertensive agents: May enhance blood‑pressure‑lowering effect. - SSRIs or other serotonergic drugs: Potential for serotonin syndrome. - Other dopaminergic agents: May increase risk of dyskinesia.



