GNH USA

Europe — EMA

Madopar Quick

GNH USA supplies Madopar Quick (Levodopa/Benserazide), a Levodopa/Dopa decarboxylase inhibitor for Parkinson's disease and Parkinsonian syndrome.

Benserazide Hydrochloride, Levodopa

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What is Benserazide Hydrochloride, Levodopa?

Levodopa/Benserazide, the active ingredient in Madopar Quick, is a Levodopa/Dopa decarboxylase inhibitor presented as an oral tablet for oral use. It is used to increase central dopamine levels in patients with Parkinson's disease and related Parkinsonian syndromes.

GNH USA supplies Madopar Quick as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Benserazide Hydrochloride, Levodopa used for?

Madopar Quick, a Levodopa/Dopa decarboxylase inhibitor, is indicated for disorders that involve dopamine deficiency.

- Parkinson's disease: improves motor control and reduces rigidity and bradykinesia. - Parkinsonian syndrome: alleviates symptoms such as tremor, stiffness, and slowed movement. - Resting tremor associated with Parkinsonism: diminishes tremor amplitude and frequency.

What are the side effects of Benserazide Hydrochloride, Levodopa?

Adverse reactions may occur with Madopar Quick and are categorized by frequency and severity.

Common Side Effects: - Nausea: mild to moderate gastrointestinal upset. - Dizziness: often related to orthostatic changes. - Headache: transient and usually resolves. - Orthostatic hypotension: drop in blood pressure upon standing. - Insomnia: difficulty initiating or maintaining sleep. - Dry mouth: reduced salivation.

Serious or Rare Side Effects: - Dyskinesia: involuntary, erratic movements. - Psychiatric disturbances: hallucinations, confusion, or depression. - Cardiac arrhythmias: irregular heart rhythms. - Severe hypotension: marked blood pressure decline requiring medical attention. - Neuroleptic malignant syndrome: rare but life‑threatening reaction. - Allergic reactions: rash, pruritus, or anaphylaxis.

What precautions apply to Benserazide Hydrochloride, Levodopa?

Before initiating therapy with Madopar Quick, consider the following safety measures.

- Blood pressure monitoring: watch for orthostatic hypotension, especially during dose titration. - Psychiatric assessment: evaluate history of psychosis or depression. - Renal function: adjust dosing in patients with impaired renal clearance. - Discontinuation: avoid abrupt withdrawal to prevent severe worsening of symptoms. - Elderly patients: start at lower doses and increase slowly. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Benserazide Hydrochloride, Levodopa interact with?

Madopar Quick may interact with several drug classes; awareness of interaction severity guides clinical decisions.

Major Interactions (Avoid): - Non‑selective MAO inhibitors: risk of hypertensive crisis. - Antipsychotics (dopamine antagonists): may diminish therapeutic effect. - High‑dose pyridoxine (vitamin B6): accelerates peripheral levodopa metabolism.

Moderate Interactions (Monitor Closely): - SSRIs and SNRIs: potential for serotonin syndrome. - Antihypertensive agents: additive blood pressure lowering. - Iron or calcium supplements: may reduce levodopa absorption if taken simultaneously.

Frequently asked questions

What is Madopar Quick used for?+
Madopar Quick contains levodopa and benserazide and is prescribed to manage the motor symptoms of Parkinson's disease and related Parkinsonian syndromes. It helps improve movement, reduce stiffness, and control tremor by increasing dopamine levels in the brain.
How does levodopa/benserazide work?+
Levodopa is a precursor that crosses the blood‑brain barrier and is converted into dopamine, the neurotransmitter deficient in Parkinson's disease. Benserazide blocks the peripheral conversion of levodopa, ensuring more reaches the brain where it is needed.
What is the usual dose of Madopar Quick?+
The dose of Madopar Quick is individualized. A qualified prescriber determines the appropriate amount and dosing schedule based on the patient's clinical condition, response, and tolerability.
Is Madopar Quick safe during pregnancy or breastfeeding?+
The safety of levodopa/benserazide in pregnancy and lactation has not been fully established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and under close medical supervision.
How do I order Madopar Quick from GNH USA?+
To request Madopar Quick, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Madopar Quick compare with other Parkinson's medications?+
Madopar Quick combines levodopa with benserazide, offering a higher proportion of levodopa to reach the brain compared with levodopa alone. Compared with dopamine agonists, it provides more direct dopamine replacement but may have a higher incidence of motor fluctuations.
What are the storage requirements for Madopar Quick?+
Madopar Quick should be stored at room temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture, heat and direct sunlight to maintain potency.
How is Madopar Quick administered?+
Madopar Quick is taken orally, usually with a small amount of food to reduce gastrointestinal upset. Tablets should be swallowed whole with water and not crushed or chewed unless specifically instructed by a healthcare professional.
What are the most serious risks associated with Madopar Quick?+
Serious risks include dyskinesia (involuntary movements), severe hypotension, psychiatric disturbances such as hallucinations, and rare but life‑threatening conditions like neuroleptic malignant syndrome. Patients should be monitored closely for these events.
Who should not use Madopar Quick?+
Madopar Quick is contraindicated in patients with known hypersensitivity to levodopa, benserazide, or any excipients, and in those taking non‑selective MAO inhibitors. Caution is also advised for individuals with narrow‑angle glaucoma, severe cardiovascular disease, or uncontrolled psychiatric disorders.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Benserazide Hydrochloride, Levodopa
Route
Oral Use
Manufacturer
Roche Pharmaceuticals A/S
Origin
EU

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