Macrovic

Macrovic, the active ingredient in Macrovic, is an electrolyte solution / osmotic laxative presented as an oral solution for oral use. It helps correct fluid loss, electrolyte imbalance and constipation. GNH USA supplies Macrovic as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Macrovic is used in the management of fluid and electrolyte disorders and constipation.

- Dehydration due to fluid loss: restores fluid balance and replaces lost electrolytes. - Electrolyte replacement: supplies sodium, potassium, chloride and bicarbonate to correct electrolyte imbalances. - Constipation: softens stools by retaining water in the intestinal lumen, facilitating bowel movements. - Bowel preparation: provides an osmotic effect to cleanse the colon prior to diagnostic procedures.

Macrovic may be associated with a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Abdominal bloating: feeling of fullness or distension in the abdomen. - Nausea: mild to moderate sensation of wanting to vomit. - Diarrhea: loose or watery stools. - Flatulence: increased intestinal gas.

Serious or Rare Side Effects: - Severe dehydration: excessive fluid loss leading to hypotension. - Electrolyte disturbances: significant hypernatremia or hyperkalemia. - Allergic reaction: rash, itching, swelling, or difficulty breathing.

When prescribing Macrovic, consider the following precautions. - Assess hydration status: evaluate fluid loss before initiating therapy. - Monitor electrolytes: check serum sodium, potassium, chloride and bicarbonate levels regularly. - Use with caution in renal impairment: adjust volume to avoid overload. - Avoid in patients with intestinal obstruction: risk of worsening blockage. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Macrovic can interact with other medications that affect fluid and electrolyte balance.

Major Interactions (Avoid): - Concomitant use with other osmotic laxatives: may cause severe electrolyte loss. - High-dose potassium supplements: risk of hyperkalemia.

Moderate Interactions (Monitor Closely): - Diuretics: may amplify fluid and electrolyte shifts. - Antihypertensive agents: potential for additive blood pressure reduction due to volume changes. - NSAIDs: can affect renal function, altering electrolyte handling.