GNH USA

Europe — EMA

Macrogol Plus Elektrolyte Dexcel

GNH USA supplies Macrogol Plus Elektrolyte Dexcel (Macrogol 3350), an osmotic laxative for constipation and bowel disorders.

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350

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What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Macrogol 3350, the active ingredient in Macrogol Plus Elektrolyte Dexcel, is an osmotic laxative presented as an oral solution for oral use. It is indicated for the relief of constipation in adults and children, helping to soften stool and promote regular bowel movements.

GNH USA supplies Macrogol Plus Elektrolyte Dexcel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution. This ensures reliable supply chains and timely delivery to end‑users.

What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 used for?

Macrogol Plus Elektrolyte Dexcel is an osmotic laxative used to manage constipation and related bowel motility disorders.

Constipation: softens stool and facilitates regular bowel movements in adults and children. Opioid‑induced constipation: counteracts opioid‑related reduced gut motility, improving stool passage. Post‑operative ileus: assists in restoring bowel function after abdominal surgery by drawing water into the intestinal lumen.

What are the side effects of Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Macrogol Plus Elektrolyte Dexcel may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Abdominal bloating - Flatulence - Nausea - Diarrhea

Serious or Rare Side Effects: - Electrolyte imbalance (e.g., hyponatremia, hypokalemia) - Severe dehydration - Allergic reaction (rash, itching, swelling)

What precautions apply to Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

When using Macrogol Plus Elektrolyte Dexcel, consider the following precautions.

Renal function assessment: evaluate kidney function before initiating therapy, especially in patients with renal impairment. Electrolyte monitoring: check serum electrolytes periodically during prolonged use. Bowel obstruction caution: avoid use in patients with known or suspected mechanical obstruction. Hypersensitivity warning: discontinue if signs of allergic reaction such as rash or swelling appear. Elderly dose consideration: start with the lowest effective dose in older adults. Store at ambient temperature: keep the solution in the original container, protect from moisture and direct sunlight.

What does Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 interact with?

Potential drug interactions should be reviewed before prescribing Macrogol Plus Elektrolyte Dexcel.

Major Interactions (Avoid): - Concomitant use with other osmotic laxatives: may cause excessive fluid loss. - Use with potent diuretics: increased risk of electrolyte disturbances. - Combination with mineral oil: may reduce laxative efficacy.

Moderate Interactions (Monitor Closely): - Opioid analgesics: may diminish laxative effect, requiring dose adjustment. - Anticholinergic agents: may lessen gastrointestinal motility, reducing product effectiveness.

Frequently asked questions

What is Macrogol Plus Elektrolyte Dexcel used for?+
Macrogol Plus Elektrolyte Dexcel is an oral osmotic laxative indicated for the relief of constipation. It works by increasing the water content of stool, making it softer and easier to pass, and is used in both adult and pediatric patients with functional or chronic constipation.
How does macrogol 3350 work?+
Macrogol 3350 creates an osmotic gradient in the intestinal lumen that draws water into the bowel. The added electrolytes help maintain fluid balance while the increased stool water softens the feces and stimulates peristalsis, facilitating natural bowel movements without systemic absorption.
What determines the usual dose of Macrogol Plus Elektrolyte Dexcel?+
The appropriate dose is individualized by the prescribing clinician based on the patient’s age, severity of constipation, renal function, and response to therapy. The prescriber will select the volume of oral solution that provides the required amount of macrogol 3350 and electrolytes for each specific case.
Is Macrogol Plus Elektrolyte Dexcel safe during pregnancy or breastfeeding?+
Safety data in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified health professional after evaluating the clinical situation.
How do I order Macrogol Plus Elektrolyte Dexcel from GNH USA?+
Enquiries can be submitted through the product page on gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details and any necessary import documentation.
How does Macrogol Plus Elektrolyte Dexcel compare with other laxatives?+
Compared with stimulant laxatives, macrogol 3350 works locally by osmotic water retention rather than stimulating intestinal nerves, resulting in a gentler effect and lower risk of cramping. Unlike bulk‑forming agents, it does not rely on dietary fiber and can be used when fluid intake is limited, while the added electrolytes help prevent imbalances.
What are the storage and handling requirements for this product?+
Store the oral solution at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture, direct sunlight and extreme temperatures. Do not freeze the solution, and ensure the label remains legible throughout its shelf life.
How is Macrogol Plus Elektrolyte Dexcel administered?+
The product is taken orally as a measured volume of the liquid solution. It should be consumed with a glass of water or other fluid, and the dose may be adjusted by the prescriber according to the patient’s response and clinical needs.
What are the most serious risks associated with this medication?+
Serious adverse events, although rare, include significant electrolyte disturbances such as hyponatremia or hypokalemia, severe dehydration, and allergic reactions that may present as rash, itching, swelling or anaphylaxis. Prompt medical attention is required if any of these symptoms develop.
Who should not use Macrogol Plus Elektrolyte Dexcel?+
The product should be avoided in individuals with known hypersensitivity to macrogol or any of the electrolyte components, in patients with mechanical bowel obstruction, and in those with severe renal impairment where electrolyte handling is compromised. A healthcare professional should assess suitability before initiation.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Route
Oral Use
Manufacturer
Dexcel Pharma Gmbh
Origin
EU

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