GNH USA

Europe — EMA

Macrogol Balance Ratiopharm

GNH USA supplies Macrogol Balance Ratiopharm (Macrogol 3350), an osmotic laxative for constipation and bowel preparation. Request a quote for global supply.

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350

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What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Macrogol 3350, the active ingredient in Macrogol Balance Ratiopharm, is an osmotic laxative presented as an oral powder for solution for oral use. It treats constipation and assists in bowel preparation for diagnostic procedures in adults. GNH USA supplies Macrogol Balance Ratiopharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 used for?

Macrogol Balance is an osmotic laxative used to manage conditions related to bowel motility.

- Constipation: provides gentle, water‑based stool softening to facilitate regular bowel movements. - Bowel preparation for colonoscopy: clears the intestinal tract to improve visualization during endoscopic procedures. - Chronic idiopathic constipation: maintains long‑term bowel regularity in patients with persistent constipation.

What are the side effects of Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Macrogol Balance may cause several adverse reactions, most of which are mild and transient.

Common Side Effects: - Abdominal bloating - Flatulence - Nausea - Diarrhea

Serious or Rare Side Effects: - Electrolyte imbalance (e.g., hypernatremia, hypokalemia) - Severe abdominal pain - Allergic reaction (rash, angioedema)

What precautions apply to Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

When prescribing Macrogol Balance, consider the following safety measures.

- Renal impairment: monitor electrolyte levels and fluid status. - Heart failure: avoid excessive fluid load. - Pregnancy: consult a healthcare professional before use. - Elderly patients: start with a lower dose and assess tolerance. - Concomitant diuretic therapy: watch for electrolyte disturbances. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 interact with?

Macrogol Balance can interact with other medicines; awareness of the interaction level is important.

Major Interactions (Avoid): - Potassium‑sparing diuretics: risk of hyperkalemia. - Lithium: may increase lithium serum concentrations. - Other osmotic laxatives: additive effect leading to dehydration.

Moderate Interactions (Monitor Closely): - Sodium‑containing antacids: may increase sodium load. - ACE inhibitors: monitor renal function and electrolytes. - Loop or thiazide diuretics: watch for shifts in electrolyte balance.

Frequently asked questions

What is Macrogol Balance Ratiopharm used for?+
Macrogol Balance Ratiopharm is an oral osmotic laxative indicated for the relief of occasional constipation and for bowel cleansing prior to diagnostic procedures such as colonoscopy. The formulation combines macrogol 3350 with electrolytes to promote gentle stool softening while maintaining fluid and electrolyte balance.
How does macrogol 3350 work in the body?+
Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is not absorbed from the gastrointestinal tract. It retains water in the intestinal lumen by creating an osmotic gradient, which softens the stool and increases its volume, thereby stimulating peristalsis and facilitating bowel movements.
What is the usual dose of Macrogol Balance Ratiopharm?+
The dose of Macrogol Balance Ratiopharm is individualized by the prescribing healthcare professional based on the patient’s condition, age, and response. The prescriber determines the appropriate amount of powder to dissolve in water and the frequency of administration.
Is Macrogol Balance safe to use during pregnancy or breastfeeding?+
Safety data for macrogol 3350 during pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and always under the guidance of a qualified healthcare provider.
How do I order Macrogol Balance Ratiopharm from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Macrogol Balance compare with other laxatives such as lactulose?+
Macrogol Balance uses macrogol 3350, an osmotic agent that draws water into the colon without being metabolised, whereas lactulose is a synthetic disaccharide that is fermented by colonic bacteria to produce acids and osmotic pressure. Macrogol generally provides a faster onset, less gas production, and more predictable electrolyte balance compared with lactulose.
What are the storage and handling requirements for Macrogol Balance?+
Store the product at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in its original packaging until use to preserve product integrity.
How is Macrogol Balance administered?+
The powder is reconstituted by dissolving the prescribed amount in a measured volume of water, typically 200 ml, and the solution is taken orally. It should be consumed promptly after preparation and may be followed by additional fluid intake as advised by the prescriber.
What are the most serious risks associated with Macrogol Balance?+
Serious risks include significant electrolyte disturbances such as hypernatremia or hypokalemia, severe abdominal pain, and rare allergic reactions that may manifest as rash, angioedema, or anaphylaxis. Patients should seek immediate medical attention if any of these symptoms occur.
Who should not use Macrogol Balance Ratiopharm?+
Macrogol Balance should be avoided in individuals with known or suspected intestinal obstruction, perforation, severe renal impairment, uncontrolled heart failure, or a documented hypersensitivity to macrogol or any of the electrolyte components.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Route
Oral Use
Manufacturer
Ratiopharm Gmbh
Origin
EU

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