Macmiror Complex

Nystatin, the active ingredient in Macmiror Complex, is an antifungal presented as a vaginal formulation for local use. It targets fungal infections of the vagina and is indicated for the treatment of vaginal candidiasis, bacterial vaginosis, and trichomoniasis, offering a broad spectrum of activity against fungi, bacteria, and protozoa in adult women.

GNH USA supplies Macmiror Complex as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies, and clinics across EU and global markets under stringent quality standards.

Macmiror Complex combines nystatin and nifuratel, delivering antifungal and antiprotozoal activity for vaginal infections. - Vaginal candidiasis: eliminates Candida species and relieves itching, discharge and irritation. - Bacterial vaginosis: reduces pathogenic bacterial overgrowth and helps restore normal vaginal flora. - Trichomoniasis: eradicates Trichomonas vaginalis, improving clinical symptoms and preventing recurrence.

Local administration of Macmiror Complex may be associated with several adverse reactions.

Common Side Effects: - Vaginal irritation or burning sensation. - Itching or pruritus in the treated area. - Abnormal vaginal discharge. - Unpleasant odor from the product. - Mild allergic rash on application. - Temporary discomfort during insertion.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling, difficulty breathing. - Persistent or worsening vaginal ulceration. - Significant swelling or pain persisting beyond 48 hours. - Systemic absorption leading to gastrointestinal upset. - Rare cases of secondary infection requiring medical attention.

Before using Macmiror Complex, consider the following safety measures. - Pregnancy: consult a healthcare professional before use. - Breastfeeding: discuss potential risks with a physician. - Allergy: avoid if known hypersensitivity to nystatin, nifuratel or any excipients. - Concurrent vaginal products: do not use other intravaginal medications simultaneously without medical advice. - Immunocompromised patients: use with caution and monitor closely. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Macmiror Complex may interact with other agents; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid): - Concurrent use of other intravaginal antifungal or antiprotozoal agents, which may increase local irritation. - Systemic antifungal therapy that could potentiate toxicity.

Moderate Interactions (Monitor Closely): - Antibiotics that alter vaginal flora, potentially affecting efficacy. - Hormonal contraceptives: no direct interaction, but monitor for any changes in vaginal symptoms. - Immunosuppressants: observe for reduced infection control. - Topical steroids applied vaginally: may mask irritation signs.