GNH USA

Europe — EMA

Liposic

GNH USA supplies Liposic (Carbomer), a excipient for ophthalmic formulations that enhance viscosity and ocular comfort. Request a quote for global supply.

Carbomer

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What is Carbomer?

Carbomer, the active ingredient in Liposic, is an excipient presented as a gel‑forming agent for ocular use. It acts as a viscosity enhancer, creating a stable, lubricating matrix that prolongs drug residence time on the eye surface and supports comfortable administration.

GNH USA supplies Liposic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable logistics for bulk and unit‑dose requirements. The company also offers regulatory support and documentation for import across regions.

What is Carbomer used for?

Liposic, containing carbomer, is employed as a viscosity‑enhancing excipient in ophthalmic formulations to improve ocular surface comfort. - Dry eye syndrome: provides prolonged lubrication and reduces tear evaporation. - Post‑operative eye care: maintains drug contact time after ocular surgery, supporting healing. - Contact lens wear: stabilizes tear film and alleviates discomfort during lens use. - Allergic conjunctivitis: helps retain antihistamine agents on the ocular surface for better symptom control. - Ocular drug delivery: serves as a gel matrix to facilitate sustained release of active pharmaceuticals.

What are the side effects of Carbomer?

Carbomer‑based ophthalmic products are generally well tolerated, but local ocular reactions can occur.

Common Side Effects: - Transient ocular irritation: mild burning or stinging upon instillation. - Temporary blurred vision: visual acuity may be briefly reduced. - Tear film disturbance: occasional increased tearing. - Foreign body sensation: feeling of grit in the eye. - Mild redness: slight conjunctival hyperemia. - Temporary discomfort: brief sensation of heaviness.

Serious or Rare Side Effects: - Severe allergic reaction: swelling, redness, or hives requiring medical attention. - Corneal ulceration: rare but serious ocular surface damage. - Infection risk: rare microbial contamination leading to keratitis. - Persistent inflammation: prolonged ocular redness or pain. - Vision loss: extremely rare, associated with severe corneal involvement. - Anaphylaxis: life‑threatening systemic reaction, though exceedingly uncommon.

What precautions apply to Carbomer?

When using Liposic, consider the following safety measures. - Assess patient history: verify no known allergy to carbomer or related polymers. - Monitor ocular response: observe for irritation or redness after first application. - Use with caution in compromised corneas: patients with epithelial defects may experience increased discomfort. - Avoid concurrent use with preservative‑rich drops: may increase irritation potential. - Discontinue if severe reaction occurs: seek ophthalmologic evaluation promptly. - Store at room temperature: keep in original container, protect from moisture and direct sunlight.

What does Carbomer interact with?

Carbomer may interact with other ophthalmic products, affecting tolerability or formulation stability.

Major Interactions (Avoid): - Co‑administration with high‑concentration preservative eye drops: can exacerbate ocular irritation. - Mixing with acidic solutions: may destabilize the gel matrix.

Moderate Interactions (Monitor Closely): - Use with other viscous gels: may alter drug distribution and viscosity. - Concurrent use of contact lens solutions containing surfactants: could affect lens comfort. - Application before intraocular procedures: may interfere with surgical field clarity.

Frequently asked questions

What is Liposic used for?+
Liposic is an ophthalmic excipient that contains carbomer, a polymer used to increase the viscosity of eye drops and gels. By forming a gel‑like matrix, it prolongs the residence time of the formulation on the ocular surface, improving lubrication, comfort, and the effectiveness of active drugs delivered in the same product.
How does carbomer work?+
Carbomer is a high‑molecular‑weight acrylic acid polymer that swells in water to create a cross‑linked hydrogel. This hydrogel thickens the solution, allowing it to adhere to the eye’s surface, slow tear turnover, and maintain a stable tear film. The resulting increased contact time helps active ingredients remain effective longer.
What is the usual dose of Liposic?+
The dose of Liposic is determined by the prescribing ophthalmologist based on the specific formulation and therapeutic need. Because it is an excipient rather than an active drug, the amount used is incorporated into the overall volume of the eye drop or gel prescribed for the patient.
Is Liposic safe in pregnancy or breastfeeding?+
Systemic absorption of carbomer from ophthalmic use is minimal, and no specific teratogenic effects have been reported. However, safety data are limited, so the prescriber should evaluate the risk‑benefit ratio for each pregnant or nursing patient before recommending Liposic‑containing products.
How do I order Liposic from GNH USA?+
To order Liposic, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and the necessary import documentation.
How does Liposic compare with the main alternative excipient?+
The most common alternative to carbomer in ophthalmic gels is hyaluronic acid, which also provides lubrication but has a different rheological profile. Carbomer typically yields a higher viscosity at lower concentrations, offering a firmer gel, whereas hyaluronic acid may be more comfortable for patients with severe dryness but can be less stable in some formulations.
What are the storage and handling requirements for Liposic?+
Liposic should be stored at room temperature, preferably below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations. Ensure the container is tightly closed to prevent contamination and maintain the integrity of the gel matrix.
How is Liposic administered?+
Liposic is supplied as part of an ophthalmic solution or gel. The product is instilled directly onto the ocular surface according to the prescribing clinician’s instructions, typically using a sterile dropper or applicator. Patients should avoid touching the tip of the container to the eye or surrounding tissues.
What are the most serious risks associated with Liposic?+
While generally well tolerated, the most serious risks include severe allergic reactions such as swelling, hives, or anaphylaxis, and rare corneal ulceration or infection that can threaten vision. Any signs of intense redness, pain, vision loss, or systemic allergic symptoms require immediate medical attention.
Who should not use Liposic?+
Individuals with a known hypersensitivity to carbomer or any component of the formulation should avoid Liposic. Patients with active corneal ulcers, severe ocular surface disease, or those who have experienced prior severe reactions to similar ophthalmic gels should also be excluded unless a specialist advises otherwise.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Carbomer
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

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