Lipoplus

Omega-3-Acid Triglycerides, the active ingredient in Lipoplus, is a intravenous lipid emulsion presented as a sterile intravenous solution for intravenous use. It provides essential fatty acids and calories to patients who require parenteral nutrition or supplementation of essential fatty acids.

GNH USA supplies Lipoplus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Lipoplus is used in clinical settings that require intravenous delivery of essential fatty acids and caloric support. - Parenteral nutrition: supplies calories and essential fatty acids for patients unable to receive enteral feeding. - Essential fatty acid deficiency: corrects deficiency in patients on long‑term lipid‑restricted diets. - Critical care nutrition: supports energy needs of critically ill or post‑surgical patients receiving total parenteral nutrition.

Lipoplus may be associated with a range of infusion‑related reactions.

Common Side Effects: - Hypertriglyceridaemia: elevated serum triglyceride levels. - Fever or chills during infusion. - Infusion site erythema or pain. - Mild thrombocytopenia. - Transient increase in liver enzymes. - Fat overload syndrome in prolonged high‑dose use.

Serious or Rare Side Effects: - Anaphylactic or severe allergic reactions, especially in patients with soy or fish oil sensitivity. - Acute pancreatitis. - Severe hepatic dysfunction or steatosis. - Pulmonary complications such as fat embolism. - Coagulopathy due to lipid‑induced platelet dysfunction. - Sepsis related to contaminated infusion sets.

When using Lipoplus, clinicians should observe several safety measures. - Assess triglyceride levels: monitor serum triglycerides regularly during therapy. - Monitor liver function: watch for hepatic steatosis or enzyme elevation. - Check for allergy: screen patients for known soy or fish oil hypersensitivity. - Use aseptic technique: ensure sterile preparation and administration. - Avoid in patients with severe hyperlipidaemia: contraindicated due to risk of fat overload. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Lipoplus can interact with other therapies that affect lipid metabolism or increase lipid load.

Major Interactions (Avoid): - Co‑administration with other intravenous lipid emulsions: cumulative lipid load may cause fat overload syndrome. - High‑dose propofol infusion: both provide lipids, increasing risk of hypertriglyceridaemia.

Moderate Interactions (Monitor Closely): - Systemic corticosteroids: may elevate serum triglycerides, requiring monitoring. - Heparin therapy: can release lipoprotein lipase, altering lipid metabolism. - Certain chemotherapeutic agents (e.g., cyclophosphamide): may increase hepatic stress when combined.